Ibufen: instructions for use. Ibufen: instructions for use and reviews Ibufen suspension instructions for use for children

Ibufen suspension is often prescribed to children as an antipyretic and pain reliever. It effectively reduces high fever, and can be taken by babies starting from infancy.

Mothers often call this medicine syrup, probably because it is sweet. In fact, syrup is a concentrated sugar solution. And Ibufen is a suspension, i.e. a suspension of dry insoluble matter. Therefore, be sure to shake the bottle well before use.

Ibufen has antipyretic, analgesic and anti-inflammatory effects.

Action

Ibufen is a non-steroidal anti-inflammatory drug, often abbreviated as NSAID. Non-steroidal means non-hormonal.

The drug has the following effects:

• antipyretic;
• pain reliever;
• anti-inflammatory.

The active substance is ibuprofen.

The first to make itself known temperature decrease - after 30 minutes, the effect lasts 5–6 hours. Don't worry - the temperature will not drop below normal. Then comes the elimination or mitigation of pain - after about 40 minutes.

The anti-inflammatory effect appears only 3-7 days after starting to take the medicine.

Ibufen is not an antiviral or antibacterial agent.

After just 40 minutes, the child will forget about ear pain.

Indications

• increased temperature due to a post-vaccination reaction (usually due to DTP vaccination);
• increased temperature due to respiratory diseases (acute respiratory infections, ARVI, influenza, bronchitis) and their complications (otitis);
• pain due to teething;
• pain syndrome and post-traumatic inflammation with severe bruises, dislocations and sprains;
• headache;
• other conditions accompanied by fever, pain and inflammation of the joints and ligaments.

Side effects

Side effects include manifestations characteristic of the entire group of non-hormonal (non-steroidal) anti-inflammatory drugs:

Contraindications

There are contraindications to the use of Ibufen and its analogues:

• individual intolerance to ibuprofen and other drugs from this group;
• gastritis and peptic ulcer;
• hemophilia, thrombocytopenia, anemia;
• renal and liver failure;
• bronchial asthma, in combination with nasal polyps.

For asthma

Allergic reactions are possible when using any medications: such side effects are included in almost all annotations. However, when taking Ibufen (as well as other NSAIDs), be careful and attentive to children suffering from bronchial asthma. The reason is that this particular disease is often combined with intolerance to drugs in this group. If there is a need for medications, it is better to replace Ibufen with paracetamol. It is the least likely of all NSAIDs to cause exacerbation of asthma.

In patients with bronchial asthma, the suspension may increase the risk of developing bronchospasm.

Pros and cons

After becoming familiar with the side effects, it becomes scary to give medicine to a child. However, there is no need to worry too much - in practice, the drug is well tolerated by children.

Side effects appear only when therapeutic doses are exceeded and the drug is used for a long time (more than 3 weeks), as well as in children with chronic diseases that are contraindicated.

If you have a high temperature (above 38 degrees), it is better to give Ibufen, since hyperthermia itself poses a danger to the life and health of the child.

Treatment is prescribed by a doctor

Antipyretic drugs easily bring down the temperature, which is why the child’s condition quickly improves. A quick effect can lull the mother's vigilance. But we must remember that Ibufen, like other antipyretics and painkillers, fights the symptoms of the disease, but does not cure the disease.
There is no need to wait 3 days with a fever before seeing a doctor. The younger the child is, the earlier you need to sound the alarm.
A repeated increase in temperature to high levels and the need to take medication more than 3 times a day is an indication to call a doctor.

Important! Only a pediatrician can determine the cause of hyperthermia and prescribe the correct treatment, including the choice of drug and its dosage.

Taking Ibufen by young children without a doctor's prescription is justified only by the emergency of the situation and is acceptable for 1 day.

Mode of application

In order to reduce the irritating effect on the stomach walls, Ibufen should be given to the child after meals. Do not give it on an empty stomach.

Let your baby eat a large meal before drinking the slurry.

Before use, the bottle must be shaken until a homogeneous suspension is obtained.

The medicine should be stored in a dark place at room temperature.

After opening, store for no more than 3 months.

Do not use after expiration date.

Dosage

The dose of Ibufen is determined at the rate of 5–10 mg of suspension per kilogram of body weight.

For those who do not have scales, if the baby is not obese or severely underweight, you can focus on age and average age weight:

• from 3 to 6 months. (6–8 kg) - single dose 1.5–2 ml;
• from 6 months up to 12 months (7–9 kg) - single dose 2–2.5 ml;
• from 1 year to 3 years (10–15 kg) - single dose 2.5–5 ml;
• from 4 years to 6 years (16–20 kg) - single dose 5–10 ml;
• from 7 years to 10 years (20–30 kg) - single dose 10 ml.

If the temperature is effectively reduced, there is no point in repeating the dose. It is justified only when the temperature rises again above 38 degrees.

When using the product again, try to give it at intervals of at least 4 hours (preferably 6 hours) and no more than 3-4 times a day.

Release form

Ibufen labeled “D”, intended for children from 3 months, Available in 120 ml bottles as a sugar-free suspension with orange flavor for oral administration. The box contains one bottle and a measuring device (spoon or dispenser syringe).

1 ml contains 20 mg of ibuprofen, 5 ml - 100 mg.

Ibufen without the “D” label is intended for children from 6 months of age, is available in bottles in the form of a suspension with sucrose and orange flavor, weighing 100 g, with a measuring spoon; 5 ml contains 100 mg of ibuprofen.

Ibufen Ultra - for adults only.

Ibufen labeled “ultra” is available in soft gelatin capsules, contains 200 mg of ibuprofen per capsule and is intended for adults.

Production

The drug is produced in Poland. There is also an official representative office of the manufacturer in Russia (JSC Akrikhin) and in Kazakhstan (JSC Khimpharm).

Price

In different cities of Russia, the average price of a bottle is from 80 to 100 rubles. The medicine can be bought in pharmacies without a prescription.

Analogues

The need to use anti-inflammatory non-steroidal drugs in childhood arises quite often. Such drugs help eliminate pain and fever, so they are always present in the home medicine cabinet if there is a small child at home. One of the most popular drugs in this group is Ibuprofen. Especially for babies Available in the form of rectal suppositories. Not everyone knows in what situations this medication is prescribed to children in the first years of life and in what dose it can be used for infants.

Release form

Ibuprofen suppositories are characterized by an elongated shape, smooth surface and white color. They are placed in blister packs of 5 pieces, and one pack includes 10 suppositories.

Compound

The active ingredient of the suppositories is called the same as the drug, ibuprofen. Its dosage in one suppository is 60 mg. In order for the drug to have a specific shape and be easily administered into the rectum, solid fats were added to its composition. There are no other auxiliary components in this medicine.

Operating principle

The drug inhibits the formation of prostaglandins - substances that support the inflammatory process, participate in the conduction of pain impulses and contribute to an increase in body temperature. That is why the medicine has antipyretic and analgesic effects, as well as the ability to reduce the manifestations of inflammation. The effect of the suppositories after administration of the medication into the intestines lasts up to 8 hours.

Indications

The medicine is prescribed:

• To reduce high body temperature - as a symptom of ARVI, chickenpox, scarlet fever, measles and other infections.
• At elevated temperatures - as a reaction to vaccination.
• For moderate or mild pain - for example, if the baby has a sore throat due to a sore throat or is teething.

At what age is it allowed to take it?

The drug is not prescribed to infants under 3 months. If the baby is already 3 months old, the use of Ibuprofen is acceptable, but after consultation with a doctor. In this case, medicine in the form of suppositories is most often prescribed to children under 2 years of age, since a child aged 2 years and older requires a higher single dosage, which is provided by the suspension.

Contraindications

The medicine is not used in the following cases:

• If your baby is diagnosed with a gastrointestinal ulcer, bleeding from the stomach or intestines, or inflammation of the intestines.
• If a child develops urticaria, allergic rhinitis or bronchial asthma during treatment with non-steroidal anti-inflammatory drugs.
• If a small patient has a blood disease - for example, hemophilia.
• If the child's kidney or liver function is impaired.
• With reduced hearing.
• If you are intolerant to ibuprofen and other anti-inflammatory drugs with a non-steroidal structure.

Side effects

The use of suppositories very rarely provokes the appearance of:

• Skin itching urticaria, bronchospasm and other allergic reactions.
• Nausea, feelings of discomfort in the abdomen, loose stools and other negative symptoms from the gastrointestinal tract.
• Insomnia, headache, restlessness or dizziness.
• Increased heart rate or increased blood pressure.
• Decrease in the number of blood cells.
• Kidney dysfunction.

Instructions for use

The drug is used rectally - in a dosage that depends on the age and weight of the small patient:

• Baby from 3 to 9 months if you weigh less than 8 kg, administer 1 suppository three times a day (with an interval of 6-8 hours). It is permissible to administer only 3 suppositories per day to a child of this age, which corresponds to a maximum daily dosage of 180 mg.
• Child over 9 months to 2 years of age with a weight of 8 to 12.5 kg, the drug is prescribed at intervals of 6 hours. Such a baby can be administered 1 suppository into the rectum four times a day (maximum 240 mg of ibuprofen per day).

If the baby has a fever after vaccination, then the suppository is placed once, and if necessary, another suppository is administered after 6 hours.

The duration of treatment with Ibuprofen suppositories depends on the purpose of use. If the drug is used for fever, it should be administered for a maximum of 3 days in a row. If the product is supposed to help with pain, then the duration of use is up to 5 days. You cannot use the medicine for longer. If symptoms persist, you need to consult a doctor to select another therapy.

Overdose

Exceeding the dose of Ibuprofen can lead to nausea, headache, rapid heartbeat, abdominal pain and other symptoms. If they appear, you should immediately show the child to the doctor.

Interaction with other drugs

Ibuprofen affects treatment with angiocoagulants, diuretics, other painkillers, glucocorticoids and many other medications, so the use of suppositories for children who are taking any other medications should be monitored by a pediatrician.

Terms of sale and storage

Ibuprofen in the form of suppositories is an over-the-counter drug, so it is freely sold in pharmacies. The average price for a pack of 10 suppositories is 60-70 rubles. This medicine should be stored at home at room temperature, in a place hidden from the sun and moisture. The shelf life of the medicine is 2 years.

Reviews

About the use of suppositories occurs a lot of positive feedback. Mothers praise the drug in this form because it can be easily used for infants, the suppository is easy to administer, and there are no harmful chemical additives in this medication. In addition, the advantage of this “Ibuprofen” is its longer action (compared to the suspension), and side effects when using suppositories are extremely rare.

Analogues

Instead of suppositories, other suppositories can be used, the action of which leads to a decrease in body temperature or a decrease in pain, for example:

• "Nurofen". Such suppositories are also made on the basis of ibuprofen, and 1 suppository contains 60 mg of the active compound. They are prescribed for fever in babies over 3 months old.
• "Cefekon D". The action of this medication is provided by paracetamol. Such suppositories are prescribed to children older than one month.
• "Panadol". The main component of such suppositories is also paracetamol. In childhood they are prescribed from 3 months.

When a child has a fever, pediatricians often prescribe Ibufen syrup for children. Instructions for use recommend using this medicine as an antipyretic and analgesic. The drug belongs to non-steroidal anti-inflammatory drugs (NSAIDs). In the pharmacy chain you can find 2 forms of suspension: “Ibufen” and “Ibufen D”. These types of syrups have the same pharmacological effect, but the drug with the letter “D” is intended for the treatment of children.

Composition of the drug

The active component of the drug is the non-steroidal analgesic ibuprofen. One bottle of liquid (100 ml) contains 2 g of the drug. In addition, Ibufen baby syrup contains additional ingredients specified in the instructions for use. Auxiliary components may vary slightly depending on the manufacturer of the drug. The syrup does not contain sugar; some types of suspension contain group E dyes.

The white or yellow suspension is bottled in 100 ml bottles. Each package comes with a spoon or syringe for dosing. The taste of Ibufen syrup depends on the type of flavoring. Most often you can find a drug with the smell of orange in pharmacies. A suspension with raspberry and strawberry flavors is also available.

How does syrup affect the body?

According to the description, Ibufen syrup has antipyretic, analgesic and anti-inflammatory effects. This is due to the effect of ibuprofen on metabolic processes in the body. The active component of the drug inhibits the activity of arachidonic acid, and this, in turn, reduces the production of prostaglandins, which play a major role in the occurrence of inflammatory processes and febrile reactions.

After taking the suspension orally, ibuprofen is quickly absorbed from the gastrointestinal tract into the blood. If a child takes the medicine with food, absorption may be slightly slower. The drug is then processed in the liver and removed from the body, mostly through urine. Within 3 hours after administration, half the dose of the medicine is eliminated.

Within half an hour after using Ibufen for children, the child’s temperature begins to decrease. And after 2-3 hours the therapeutic effect reaches its maximum.

Indications for use

If a child needs to bring down a high fever and relieve pain, the doctor can prescribe Ibufen syrup for children. Instructions for use recommend prescribing the drug in the following cases:

• viral colds;
• childhood infections accompanied by fever (except chickenpox);
• inflammation of the throat (sore throat, pharyngitis, laryngitis);
• reaction to vaccination with fever;
• pain in the ears due to inflammation;
• pain during teething and after dental interventions;
• soreness after muscle and bone injuries;
• headache, migraine.

To alleviate the child's condition, reduce fever and pain, pediatricians prescribe Ibufen syrup. Indications for use are many infectious and viral diseases, but it is important to remember that this is a medicine for symptomatic therapy. It does not affect the cause of the disease, but only relieves unpleasant manifestations.

When should you not take syrup?

The drug should be given to a child only on the recommendation of a pediatrician. Not all children can take NSAID medications. Instructions for use of Ibufen syrup for children prohibit the use of the medicine in the following cases:

• hypersensitivity to ibuprofen;
• blood diseases accompanied by reduced coagulation;
• history of allergic manifestations (bronchial asthma, urticaria, hay fever) associated with taking aspirin;
• chicken pox (the use of NSAIDs can cause inflammation of the connective tissue - bacterial fasciitis);
• ulcerative processes in the digestive organs;
• severe pathologies of the kidneys and liver;
• excess potassium in the body (if this deviation is confirmed by tests);
• pathologies with bleeding;
• intestinal inflammation;
• enzyme disorders (malabsorption of glucose-galactose and sucrose-isomaltose, fructose intolerance).

The drug is not prescribed to children under 3 months. When prescribing medication to a child under one year of age, the dosage must be carefully calculated and observed. Adult women should not be treated with children's Ibufen during pregnancy and lactation; they should avoid products containing ibuprofen.

Sometimes caution is necessary when prescribing medication. Reduced dosages and regular monitoring of the child's reaction to the drug may be required. These increased precautions are necessary in the following cases:

1. If your child has heart disease or high blood pressure.
2. For severe pathologies of any internal organs.
3. With increased bilirubin in the blood test.
4. For autoimmune diseases (systemic lupus erythematosus, rheumatoid arthritis, scleroderma).
5. If the presence of the gastric bacterium Helicobacter pylori is detected.
6. If the child is simultaneously taking glucocorticosteroids, medications to reduce blood clotting, and medications against blood clots.

Undesirable effects

In most cases, the medicine is well tolerated by children. However, the instructions for using Ibufen syrup warn that in rare cases, side effects from various organs and systems of the body are possible.

Children with allergies may develop skin rashes such as urticaria and itching, bronchospasm, and runny nose. Such phenomena usually occur in babies with hypersensitivity to aspirin. Typically, patients who are allergic to acetylsalicylic acid also react poorly to other non-steroidal anti-inflammatory drugs. In such cases, Ibufen D should be discontinued. In rare cases, more severe allergic reactions are possible, such as anaphylactic shock, angioedema. Therefore, before using the product, you must make sure that the child does not have NSAIDs.

The child's gastrointestinal tract may be too sensitive to the effects of the drug. In this case, phenomena such as nausea, vomiting, abdominal pain, diarrhea or constipation, and increased formation of gases are observed. Young children may develop mouth ulcers, similar to stomatitis. Taking the medication for too long can negatively affect the condition of the liver and pancreas and provoke the development of inflammatory diseases of these organs.

If a child has problems with the heart or blood vessels, then the medicine must be taken with extreme caution. Otherwise, there is a risk of exacerbation of chronic pathology. In children prone to arterial hypertension, blood pressure may increase.

An alarming side effect from the respiratory system is shortness of breath. This symptom may be associated with the development of bronchospasm due to an allergic reaction. In this case, you need to stop taking the medicine and visit a doctor to change therapy.

The child's central nervous system may react negatively to the drug. This is manifested by headache, depressed or overly excited mental state, anxiety, and drowsiness. Particular care must be taken when treating patients with autoimmune diseases. Such pathologies are often accompanied by joint pain, and parents give their children Ibufen as an analgesic. This should never be done without the advice of a doctor. There have been cases where patients with autoimmune diseases developed aseptic meningitis after taking NSAIDs.

Taking the drug can provoke renal dysfunction: excessive and frequent urination, cystitis, allergic nephritis, edema. Rare cases of acute decline in renal function have occurred.

All drugs containing ibuprofen, when taken for a long time, affect the composition of the blood. A decrease in the number of platelets and leukocytes, agranulocytosis, and a decrease in hemoglobin may be observed.

Sometimes during therapy children experience sensory disturbances. The child may complain of temporary hearing loss, noise and ringing in the ears, blurred vision, and impaired color perception.

Children may experience increased sweating after taking the medicine. It is difficult to say whether this is a side effect or the result of a sharp drop in temperature.

If a child experiences adverse events while taking the drug, you should stop using the suspension and consult a doctor.

Manifestations of overdose and poisoning

The instructions for use of Ibuprofen syrup (Ibufen) warn that if the permissible dose of the medicine is exceeded, intoxication is possible. Overdose is accompanied by the following symptoms:

• abdominal pain;
• nausea and vomiting;
• stopping breathing (apnea);
• rapid heartbeat with atrial fibrillation;
• convulsions;
• comatose state;
• drowsiness;
• lethargy;
• tinnitus;
• a sharp decrease in blood pressure;
• development of metabolic acidosis.

Overdose is especially severe in children under 5 years of age. Children experience breath holding, convulsions, and coma quickly sets in. A dosage of 400 mg of the active component of the syrup per 1 kg of a child’s weight is considered life-threatening. In such cases, it is important to call emergency help as soon as possible, rinse the stomach and give activated charcoal. Next, the doctor will conduct poisoning in a hospital or at home.

To avoid such situations, you must not only follow the recommended dosage, but also store the bottle of the drug out of the reach of children. The sweet taste of the suspension usually attracts children, and they may mistake the medicine for ordinary fruit or berry syrup. This is how poisoning often occurs.

Before use, the bottle of syrup must be shaken so that the suspension becomes homogeneous. The drug is taken orally, after meals, with water.

The dosage of Ibufen is prescribed by a doctor; the amount of syrup per day depends on the age and weight of the child. It is allowed to consume no more than 20-30 mg of ibuprofen per 1 kg of body weight per day.

Instructions for use of Ibuprofen syrup (Ibufen) recommend taking the medicine three times a day at intervals of 6-8 hours. Single doses by age are as follows:

• From 3 to 6 months - 2.5 ml of syrup.
• From 6 to 12 months - 2.5 ml (4 times a day).
• 1-3 years - 5 ml.
• 3-6 years - 7.5 ml.
• 7-9 years - 10 ml.
• 10-12 years - 15 ml.

These are approximate doses of the suspension, calculated for the average weight of the child. The doctor will determine the exact amount of the drug based on the baby’s body weight.

To avoid the development of side effects, Ibufen is not prescribed to children for a long time. To reduce the temperature, the syrup can be consumed for up to 3 days, and for pain relief - no more than 5 days.

The package with the bottle comes with a dispenser syringe. With its help, you can measure the required amount of syrup and put it into the child’s mouth. To do this you need to do the following:

1. Remove the bottle cap.
2. Insert the end of the syringe into the bottle through the hole in the neck.
3. Shake the syrup.
4. Turn the bottle upside down and draw the required amount of suspension into the syringe.
5. Remove the dispenser using a rotating motion.
6. Slowly pressing the syringe plunger, inject the suspension into the child's mouth.
7. Rinse the dispenser under water.

Interaction with other drugs

1. Other types of NSAIDs, aspirin and glucocorticoid hormones. This may increase the likelihood of side effects.
2. Diuretics and high blood pressure medications. Taking it together may reduce the effect of using Ibufen.
3. Potassium-sparing diuretics. Their combination with NSAIDs can lead to hyperkalemia.
4. Antibiotics of the quinolone group. The combination of these drugs with Ibufen can provoke seizures.
5. Antiplatelet agents, anticoagulants and antidepressants of the SSRI group. Ibuprofen potentiates their effect, which can lead to bleeding. For the same reason, it is undesirable to combine the use of syrup with the use of antiviral tablets "Zidovudine".
6. Methotrexate and Digoxin. NSAIDs enhance the effect of these drugs.
7. Immunosuppressants. Taking them together with Ibufen creates a large load on the kidneys.

Storage conditions

Instructions for use of Ibufen syrup for children recommend storing the bottle with the drug at a temperature of no more than +25 degrees. The lid must be screwed on tightly. It is important to put the suspension in a place where it is inaccessible to children.

Unopened packages of syrup can be stored for 2 years. After the bottle has been first opened, the suspension remains valid for 6 months.

Price and analogues

The price of Ibufen in pharmacies is about 90 rubles. The medicine is available without a prescription, but should be taken on the advice of a doctor.

Sometimes parents of sick children are interested in other suspensions with a similar effect. The following drugs are complete analogues of Ibufen syrup according to the active substance:

• children's suspension "Ibuprofen";
• syrup for children "Nurofen";
• Advil children's suspension.

These medicines also contain ibuprofen. The effect of these drugs is absolutely the same. In Moscow pharmacies, Ibuprofen suspension costs from 68 to 70 rubles, which is slightly lower than the price of Ibufen. Syrup for children "Nurofen" is a more expensive drug. Its price ranges from 122 to 258 rubles. These analogues are the most common.

Advil for children is very difficult to find in pharmacies. Usually it is ordered via the Internet. The drug is very expensive, about 1,500 rubles.

A complete analogue of the drug in terms of the active substance is Ibufen D Forte syrup. This is an enhanced form of the drug containing 200 mg of ibuprofen per 5 ml of suspension. The price of the drug is from 140 to 220 rubles.

You can choose children's antipyretic syrups with other active ingredients, but with a similar therapeutic effect:

• "Panadol", "Efferalgan", "Calpol" (based on paracetamol);
• "Nise" (based on nimesulide).

Parents of children often wonder which is better - ibuprofen or paracetamol. If a child has a very high temperature, then it is more effective to bring it down with Ibufen. Paracetamol-based syrups act more like analgesics, but these drugs cannot relieve severe fever.

As for suspensions based on nimesulide, they often cause a too sharp drop in temperature in babies (up to 35 degrees). However, such children's syrups are more effective against inflammation than Ibufen.

Ibufen for children has antipyretic, analgesic and anti-inflammatory effects.
The mechanism of antipyretic action is realized through the central and peripheral components. The action of Ibufenu for children raspberries is to block arachidonic acid cyclooxygenase in the central nervous system. This leads to a decrease in the synthesis of prostaglandins, as a result of which body temperature normalizes. The peripheral component of the antipyretic effect of Ibufenu® for children, raspberry, is due to the inhibition of the processes of creating prostaglandins in damaged tissues, which causes a decrease in inflammatory activity.
The effect of lowering body temperature begins within 30 minutes after using the drug, and its maximum effect appears after 3:00.
The antipyretic and analgesic effect appears earlier and in smaller doses than the anti-inflammatory effect. Ibuprofen inhibits platelet aggregation.
Pharmacokinetics.
After oral administration, more than 80% of ibuprofen is absorbed from the gastrointestinal tract, reaching maximum plasma concentrations after 1-2 hours. Binds to plasma proteins (mainly albumin) by more than 90%. The drug slowly penetrates into the joint cavity. The maximum concentration in the synovial fluid is observed 5-6 hours after oral administration.
DOES NOT accumulate in the body.
Metabolized in the liver to two inactive metabolites, which are quickly and almost completely excreted by the kidneys.
60-90% is excreted in the urine in the form of metabolites and their products in combination with glucuronic acid. A certain amount (10%) is excreted unchanged. The half-life is 2:00. After taking a single dose, the drug is completely eliminated within 24 hours.

Indications for use

Mode of application

Taking the drug in a single dose can be repeated every 6-8 hours. The maximum daily dose should not be exceeded.
Infants from 3 to 6 months (5-7.6 kg) with post-vaccination reactions: 2.5 ml of the drug, if necessary, repeat 2.5 ml after 6 hours.
The daily dose of the drug for children from 3 to 6 months should not exceed 5 ml.
In children from 3 to 6 months, the drug can be used only after consultation with the attending physician.
Ibufen can be used for no more than 3 days as an antipyretic and no more than 5 days as an analgesic.
If fever persists for more than 3 days, you should consult your doctor.
If pain persists for more than 5 days, you should consult a doctor.
Using a syringe dispenser:
1. Unscrew the cap of the bottle (press downwards and turn counterclockwise).
2. Press the dispenser firmly into the opening of the bottle neck.
3. Shake the contents of the bottle vigorously.
4. To fill the dispenser, the bottle must be turned upside down, and then carefully move the dispenser piston down, pour in the contents until the desired mark on the scale is reached.
5. Turn the bottle over to its original position and carefully remove the dispenser from it with a rotating motion.
6. Place the tip of the dispenser in the child’s mouth, and then, slowly pressing the piston, introduce the contents of the dispenser.
7. After use, the bottle should be closed by screwing on the cap, and the dispenser should be rinsed with drinking water and dried.

Side effects

Contraindications

Interaction with other drugs:
Should not be used Ibufen for children simultaneously with other NSAIDs. For example, acetylsalicylic acid reduces the anti-inflammatory effect of ibuprofen and increases side effects.
If possible, the simultaneous use of ibuprofen and diuretics should be avoided, due to the weakening of the diuretic effect and the risk of developing renal failure.
Ibuprofen reduces the hypotensive activity of vasodilators (including ACE inhibitors).
Ibuprofen enhances the effect of oral hypoglycemic agents (especially sulfonylureas) and insulin.
Inducers of microsomal oxidation (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites, increasing the risk of severe hepatotoxic reactions.
Antacids and cholestyramine reduce the absorption of ibuprofen.
Cefamandole, cefoperazone, cefotetan, valproic acid, plicamycin increase the incidence of hypoprothrombinemia.
Drugs with a myelotoxic effect increase the manifestations of hematotoxicity of the drug.
Cyclosporines and gold preparations enhance the effect of ibuprofen on the synthesis of prostaglandins in the kidneys, which is manifested by increased nephrotoxicity.
Ibuprofen increases the plasma concentration of cyclosporine and the likelihood of developing its hepatotoxic effects.
Drugs that block tubular secretion reduce excretion and increase plasma concentrations of ibuprofen.
Strengthens the effect of indirect anticoagulants, antiplatelet agents, fibrinolytics (increasing the risk of hemorrhagic complications).
Increases the blood concentration of digoxin, methotrexate and lithium preparations.
Caffeine enhances the analgesic effect of ibuprofen.

Overdose

Children under 5 years of age are especially prone to apnea, coma, and seizures.
Serious consequences associated with the toxic effect of the drug usually appear after taking a dose exceeding 400 mg/kg body weight. In case of overdose, consult a doctor immediately.
Treatment: gastric lavage (only within an hour after taking the drug), activated charcoal, alkaline drinking, symptomatic therapy (correction of acid-base status, blood pressure).

Storage conditions:
Ibufen for children should be stored out of the reach of children, protected from light at a temperature not exceeding 25°C. Shelf life - 3 years.
An opened bottle should be used within 6 months.

Release form

Compound:
Ibufen for children contains - ibuprofen 100 mg/5 ml.
Excipients: carmellose sodium - 0.97 g, macrogol glyceryl hydroxystearate - 1.14 g, sucrose - 34.2 g, glycerol - 5.7 g, magnesium aluminum silicate (veegum) - 0.57 g, propylene glycol - 1.71 g, methyl parahydroxybenzoate - 0.15 g, propyl parahydroxybenzoate - 0.0 5 g, sodium phosphate dihydrate - 0.46 g, citric acid monohydrate - 0.91 g, sodium saccharinate - 0.25 g, crospovidone - 0.14 g, orange flavor - 0.34 g, sunset yellow dye (E110) - 0.02 g, purified water - up to 100 ml.

Additionally

Main settings

Ibuprofen

Dosage form

rectal suppositories (for children)

Composition of Ibuprofen in suppository form

Active ingredient: Ibuprofen 60 mg Excipients: solid fat 516 mg.

Description

Suppositories are white or almost white, smooth, torpedo-shaped.

Pharmacotherapeutic group

Non-steroidal anti-inflammatory drug (NSAID).

Pharmacodynamics of the drug

It has analgesic, anti-inflammatory and antipyretic effects. The mechanism of action of ibuprofen is due to inhibition of the biosynthesis of prostaglandins - mediators of pain and inflammation. The effect of the drug lasts up to 8 hours.

Indications: Ibuprofen in suppository form

Ibuprofen rectal suppositories (for children) are used from 3 months of life to 2 years as an antipyretic for acute respiratory diseases, influenza, childhood infections, post-vaccination reactions and other infectious and inflammatory diseases accompanied by an increase in body temperature. The drug is used as an analgesic for pain syndrome of mild or moderate intensity, including: headaches and toothaches, neuralgia, pain in the ears and throat, pain from ligament injuries and other types of pain.

Contraindications Ibuprofen in suppository form

Ibuprofen should not be used in case of: - hypersensitivity to ibuprofen, acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (NSAIDs), as well as to other components of the drug; - bronchial asthma, urticaria, rhinitis, provoked by taking acetylsalicylic acid (salicylates) or other NSAIDs; - if a child has an ulcerative lesion of the gastrointestinal tract (GIT); - active gastrointestinal bleeding; - inflammatory bowel diseases; - confirmed hypokalemia; - blood diseases: hypocoagulation, leukopenia, hemophilia; - renal and/or liver failure ;- hearing loss.

Carefully

You should consult your doctor before using ibuprofen if your child: - is taking other painkillers; - has a history of peptic ulcers, gastritis, ulcerative colitis, gastrointestinal bleeding; - has liver or kidney disease; - is taking indirect anticoagulants (drugs for taking orally, which reduce blood clotting), drugs to lower blood pressure, glucocorticosteroids, antiplatelet agents, diuretics (drugs to increase urination), lithium drugs, methotrexate; - suffers from bronchial asthma, urticaria.

Directions for use and dosage: Ibuprofen in suppository form

Ibuprofen is a suppository specially designed for children. The drug is administered rectally. Read the instructions carefully before taking the drug. Fever (heat) and pain: The dosage for children depends on the age and body weight of the child. A single dose is 5-10 mg/kg of the child’s body weight 3-4 times a day. The maximum daily dose should not exceed 30 mg per kg of body weight of the child per day. Children aged 3-9 months (5.5 kg - 8.0 kg): 1 suppository (60 mg) 3 times within 24 hours every 6-8 hours, no more than 180 mg per day. Children aged 9 months - 2 years (8.0 kg - 12.5 kg): 1 suppository (60 mg) 4 times within 24 hours every 6 hours, not more than 240 mg per day. Post-immunization fever: one suppository for children under 1 year of age, after 1 year, if necessary, another suppository after 6 hours. Duration of treatment: - no more than 3 days as an antipyretic; - no more than 5 days as an anesthetic. If fever persists, consult your doctor. Do not exceed the indicated dose.

Side effects of the medicine

When using the drug, side effects are rare, but the following side effects may occur: From the gastrointestinal tract: nausea, vomiting, feeling of discomfort or pain in the epigastrium, laxative effect, possible occurrence of erosive and ulcerative lesions, bleeding. Allergic reactions: skin rash, itching, urticaria, exacerbation of bronchial asthma, angioedema, anaphylactoid reactions, anaphylactic shock, bronchospasm, fever, erythema multiforme exudative (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome). From the nervous system: headache, dizziness, psychomotor agitation, insomnia. The cardiovascular system: tachycardia, increased blood pressure. From the hematopoietic organs: anemia, thrombocytopenia, agranulocytosis, leukopenia. From the urinary system: impaired renal function, cystitis. If these or other side effects occur, you should stop using the drug and consult a doctor.

Overdose

Problems with an overdose are very rare, but if you accidentally exceed the recommended dose, consult a doctor immediately. Symptoms: abdominal pain, nausea, vomiting, headache, rapid eye movements (nystagmus), difficulty breathing, cyanosis of the lips and tip of the nose, bradycardia, tachycardia.

Interaction

The simultaneous use of Ibuprofen with anticoagulants can lead to an increase in their effect. Ibuprofen increases the concentration of digoxin, phenytoin, methotrexate, lithium in the blood plasma when used simultaneously with these drugs. The use of ibuprofen together with diuretics and antihypertensive drugs reduces their effectiveness. Increases the side effects of mineralocorticosteroids and glucocorticosteroids .

Release form/dosage

Rectal suppositories (for children) 60 mg.

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25 ° C. Keep out of the reach of children.