Sub simplex duration. Sab Simplex for newborns: instructions for use

Sub Simplex: instructions for use and reviews

Sab Simplex is a drug that helps reduce flatulence.

Release form and composition

Dosage form of release - suspension for oral administration: from gray-white to white, somewhat viscous, has a characteristic fruity (vanilla-raspberry) odor (in glass dark dropper bottles of 30 ml (1 ml = 25 drops), 1 bottle each - dropper in a cardboard box).

Composition of 100 ml suspension:

  • active ingredient: simethicone – 6.919 g (silicon dioxide: dimethicone 350, in a ratio of 7.5%: 92.5%);
  • additional components: raspberry flavor - 0.108 g, hypromellose - 1.5 g, carbomer - 0.6 g, sodium citrate dihydrate - 1 g, citric acid monohydrate - 0.5468 g, vanilla flavor - 0.315 g, sodium cyclamate - 0, 2 g, sodium saccharinate – 0.02 g, sodium benzoate – 0.1 g, polyglycostearyl acid esters – 1.0378 g, sorbic acid – 0.0347 g, water – 89.6189 g.

Pharmacological properties

Pharmacodynamics

By reducing the surface tension at the interface, simethicone, the active component of Sub Simplex, inhibits the formation and ensures the destruction of gas bubbles in the intestinal contents. The gases that are released during this process can be absorbed by the intestinal walls or excreted due to peristaltic activity.

In X-ray and sonography, simethicone prevents overlap and interference in images and provides better irrigation of the colon mucosa with contrast agent, preventing damage to the contrast film.

The active component of Sab Simplex changes the surface tension of gas bubbles formed in the contents of the stomach and intestinal mucus, which leads to their destruction. The released gases are absorbed into the intestinal walls or expelled during intestinal peristalsis. Simethicone removes foam physically and does not take part in chemical reactions.

Pharmacokinetics

Since simethicone is physically and chemically inert, it is not absorbed into the body and, after passing through the gastrointestinal tract, is excreted unchanged.

Indications for use

  • flatulence, increased gas formation, including those occurring during the postoperative period (as symptomatic therapy);
  • acute poisoning with detergents when they enter the stomach;
  • preparation for diagnostic studies of the gastrointestinal tract (radiography, ultrasound, esophagogastroduodenoscopy).

Contraindications

  • intestinal obstruction;
  • obstructive diseases of the gastrointestinal tract;
  • hypersensitivity to substances included in the suspension.

Instructions for use of Sab Simplex: method and dosage

Sub Simplex suspension is taken orally, preferably at the same time or after meals and, if necessary, before bedtime.

  • newborns and children under 1 year of age on artificial feeding: single dose - 15 drops (added to baby food (in each bottle) or given undiluted from a spoon before feeding). The suspension mixes well with liquids, including milk;
  • children 1-6 years old: single dose – 15 drops, simultaneously or after meals, it is possible to take an additional single dose at night;
  • children 6-15 years old: single dose – 20-30 drops, frequency of administration – 4-6 times a day (preferably at equal intervals);
  • adults: single dose – 30-45 drops, frequency of administration – 4-6 times a day (preferably at equal intervals).

The duration of the course is determined by the indications (complaints). Long-term therapy is possible.

Before taking, the bottle with Sub Simplex should be shaken vigorously. To get the suspension from the pipette, you need to turn the bottle upside down and tap on its bottom.

  • radiography: 3-6 teaspoons in the evening before the day of the study;
  • Ultrasound: 3 teaspoons in the evening before the day of the examination and 3 hours before it;
  • endoscopy: 0.5-1 teaspoon before the examination; additionally, during endoscopy, several milliliters of suspension are injected through the endoscope.

When taking the drug during preparation for research, it is recommended to remove the pipette.

Doses of Sub Simplex for poisoning with detergents are determined by the severity of the condition. The minimum recommended dose is 1 teaspoon.

Side effects

Allergic reactions may develop while taking the drug.

Overdose

There have been no cases of overdose.

special instructions

New/recurrent complaints caused by increased gas formation must be clinically confirmed.

Impact on the ability to drive vehicles and complex mechanisms

Taking the drug does not affect the ability to drive a car or perform work that requires quick reactions and increased concentration.

Use during pregnancy and lactation

According to the instructions, Sab Simplex can be used during pregnancy and during breastfeeding according to indications.

Use in childhood

The drug is used to treat children. Sab Simplex for newborns and children under one year of age who are bottle-fed is added to the bottle with food. Sub Simplex for newborns and breastfed children is given from a spoon before feeding.

Drug interactions

There are no data on the interaction of Sab Simplex with other drugs/substances.

Analogues

Analogues of Sab Simplex are: Espumisan, Kolikid, Simot, Infacol, Metsil, Kuplaton, Disflatil, Bobotik, Antiflat Lannacher,

Terms and conditions of storage

Store out of reach of children at temperatures up to 25 °C.

Shelf life – 3 years.

After birth, babies have imperfect digestive and nervous systems. The lack of enzymes necessary for digesting food affects the baby’s well-being. Until about 4 months, almost all children experience discomfort in the tummy in the form of bloating and. There are many medications to alleviate the condition of newborns, but not every medicine is suitable for all children without exception, due to physiological characteristics and allergic status. Some of the medications have side effects and almost all have contraindications.

Anti-colic drops Sab Simplex

SAB Simplex for newborns is one of the safest medicines for colic. The action of the drug is aimed at the cause of flatulence, without interfering with the biochemical processes of digestion. SAB Simplex drops for colic naturally remove gases from the body.

In what cases is SAB simplex used?

Before buying medicine for your child, be sure to consult your pediatrician. Only a doctor will determine the real cause of the baby’s anxiety, make a diagnosis and prescribe medications correctly.

Indications for use of the drug SAB Simplex:

  • physiological bloating in the intestines of newborns. The medicine will not help with infectious diseases, enzymatic disorders, although they can also be manifested by abdominal pain, bloating and crying of the child;
  • hardware examination of the gastrointestinal tract (FGDS, ultrasound, radiography, MRI, CT);
  • surfactant poisoning (detergents).

How does SAB Simplex work?

The main component included in SAB Simplex is called simethicone. is a compound of silicon dioxide with dimethylsiloxane, which has a carminative effect. Simethicone plays the role of an antifoam in the intestinal lumen. It breaks large gas bubbles into smaller ones, which are absorbed into the intestinal wall and expelled by peristaltic movements. Thus, the amount of gas in the intestinal lumen decreases and colic goes away. The drug does not enter into chemical bonds with other drugs or organic compounds of the body, and is excreted through the intestinal lumen in its original form.

How to take SAB Simplex?

  • How to give SAB simplex: The medicine is given in the form of drops; each age has its own dosage. Before use, shake the bottle and turn it down with a pipette, measuring out the required number of drops.
  • How many drops to give: To eliminate colic, children from 1 month to a year should be given 15 drops during feeding or immediately after it. If the baby is formula-fed, you can add the medicine to the bottle with food. SAB Simplex is compatible with any liquids: milk, water.
  • For kids on breastfeeding SAB simplex It is convenient to give, diluted in boiled water or milk, using the dosing part of a syringe or a teaspoon, before application.
  • How often to give SAB simplex: Doctors recommend using this medicine twice a day: during feeding - 15 drops and before bedtime - 15 drops.

If necessary, the dosage can be extended over several feedings, this applies to infants who are often put to the breast (free feeding) and artificial babies with severe colic: 10 drops per feeding, with an interval of 3 hours. According to the instructions, the drug can be given up to eight times a day.

If the use of SAB Simplex is due to preparation for a diagnostic examination, then the dosage, time and frequency of taking the drug are prescribed only by the attending physician.

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Laxatives based on lactulose (Duphalac) and the medicine SAB Simplex for constipation are taken together, since lactulose causes gas formation.

When is SAB simplex contraindicated?

Like any drug, SAB Simplex has contraindications:

  1. obstructive (impaired patency, peristalsis) gastrointestinal disorders;
  2. congenital malformations of the gastrointestinal tract with obstruction;
  3. individual intolerance.

An allergy to SAB simplex can occur as a reaction to simethicone or to its constituent flavorings and preservatives. Then you need to ask the pediatrician to choose another suitable drug for the baby.

SAB Simplex can be used during pregnancy and lactation. Since the medicine does not penetrate into the blood, it is absolutely safe for the fetus and infant.


How does SAB simplex differ from its analogues?

The average price for a package of SAB simplex for newborns is 200 – 240 rubles. The cost of such drugs on the market is approximately the same. Many analogues have gained great popularity among doctors and parents, but, nevertheless, SAB simplex has many advantages compared to them:

  1. Espumisan or SAB simplex: the active ingredient in the drugs is the same - simethicone, but in different dosages. In SAB simplex, 1 ml contains 69.19 mg of the active substance, and in Espumisan, 5 ml contains 40 mg. SAB Simplex is more convenient to use: 15 drops per dose, and Espumisan - 1 teaspoon, which is not always possible to give to a small child. Because of this, Espumisan runs out faster, with the same bottle volume as SAB simplex. It should also be noted that advertising for Espumisan is actively broadcast in the media, which has led to frequent counterfeits of the drug.
  2. Bobotik and SAB simplex: Both drugs contain simethicone, in approximately the same concentrations. Bobotik is used no more than 4 times a day, and SAB simplex can be given at every feeding. Price the first drug - from 150 rubles, which is an undoubted advantage.
  3. Baby Calm or SAB Simplex: drugs that are completely different in composition and can be used in parallel. Baby Calm contains a mixture of vegetable oils, which, in addition to the carminative effect, also have anti-inflammatory, analgesic and sedative effects. If the baby is very restless and suffers from severe colic, then Baby Calm will be a good addition to the SAB Simplex medicine.

The digestive tract of newborns is immature, and its functions are still imperfect.

The oral mucosa is rich in receptors that “turn on” the sucking reflex and the production of secretions by the salivary glands. For a formula-fed newborn, saliva is more needed for learning to swallow.

A poorly developed muscle layer and the absence of an obstacle (septum, cardiac sphincter) between the stomach and esophagus leads to the swallowing of large amounts of air during meals. The baby’s stomach is also small, and if the child is given too much food at a time, the walls become overstretched, causing pain and anxiety. Poorly developed glands and the muscular layer of the stomach also lead to increased gas formation.

Intestinal colic usually develops from three weeks of age and lasts up to three months. This period will quickly be forgotten, and you will calmly enjoy communication with your beloved baby.

Read more about Sub Simplex

The instructions for use for the drug describe that the composition of SAB Simplex is based on simethicone, which is a mixture of dimethicone and silicon dioxide. Citric acid monohydrate and flavorings (vanilla and raspberry) are listed as excipients.

You may be allergic to SAB Simplex. Before use, you should consult your pediatrician. At the first signs (redness, rash, restlessness of the baby, breathing problems), you should stop giving the drug and seek help.

Sub Simplex drops are not absorbed into the blood. This means that the drug does not “load” either the baby’s liver or kidneys. It is used from the newborn period.

This drug acts on gas bubbles and causes them to fragment. In addition, Sub Simplex partially prevents the formation of new gas bubbles from previously destroyed ones. Their remains are eliminated by peristaltic waves of the intestines along with feces, so difficult-to-remove “balls” of gases and mucus do not form.

The drug does not cause dysbacteriosis, since it does not affect the biocenosis of the internal environment of the intestine.

How to take SAB Simplex

The medicine is available in the form of a suspension for oral administration.

If bottle feeding, simply add drops to the formula.

There are several ways to give the drug if the baby is breastfed:

  1. Express a small amount of milk and add the suspension to it in the required dosage.
  2. The required amount of Sub Simplex can be dripped immediately before feeding through a teaspoon.
  3. Sub Simplex easily dissolves in liquids, so you can mix it with water (a small amount - 10 ml) and give it to your baby to drink.

The drug can be given both during and after meals. To prevent colic from interfering with your baby's sleep, you can give it before bed.

In order to eliminate increased gas formation, newborns and infants are given the drug 15 drops, which is approximately 0.6 ml of suspension.

For children from 1 year to 6 years, the dose of the drug is 15 - 20 drops. This amount of the drug must be given 2 times a day.

In more severe cases, the drug can be given every 6 hours. The drug begins to act quickly and can be given regularly for a long time.

The bottle should be in a dark place.

Which is better to choose? Sab Simplex in comparison with other colic remedies

  1. Sub Simplex or Bobotik? If your baby is experiencing mild pain, gas formation is rare and there are no mucous lumps, you can use Bobotik, because it can be used a maximum of four times a day, no more. It is also slightly cheaper than its competitor. In addition, Bobotik is allowed to be taken only from the 28th day of the baby’s life, in this it is inferior to Sub Simplex.
  2. Sab Simplex or Espumisan? This choice arises because both of them contain the active substance simethicone. Espumisan has less of this component. In addition, there is an inconvenience in maintaining the exact dosage (1 teaspoon). In some cases, you can find a fake, since Espumisan is well advertised.

It is advisable to take Espumisan for no more than 2 - 3 weeks, and Sab Simplex can be given for quite a long time.

Almost every new mother knows firsthand what colic is. In children, this is one of the most common problems, along with increased gas formation, constipation and other disorders of the gastrointestinal tract. To avoid sleepless nights and truly enjoy motherhood, you should try giving your child Sub Simplex - a safe and reliable remedy that improves intestinal function.

Composition of Sub Simplex


The active ingredient of the product is simethicone - a mixture of silicon dioxide and dimethicone 350 in a ratio of 7.5%: 92.5%. 100 ml of Sab Simplex contains 6.919 g of simethicone, as well as auxiliary components in small quantities, including:

  • sorbic acid;
  • sodium cyclamate;
  • hypromellose;
  • polyglycostearyl acid ester compounds;
  • sodium saccharinate;
  • carbomer;
  • sodium citrate;
  • lemon acid;
  • sodium benzoate;
  • vanilla and raspberry flavorings.

All these substances will not harm even a baby who is not yet a month old, but they can significantly improve his well-being.

How the drug works

Simethicone has the ability to reduce surface tension formed at the interface. This prevents the formation and ensures the destruction of gas bubbles in the lower gastrointestinal tract. In this case, gases are easily released and expelled either through peristalsis or absorbed by the intestinal walls.

In sono- and radiography of the intestine, simethicone allows you to obtain the clearest and most contrasting image, minimizing interference and recording defects. It also improves the coverage of the colonic mucosa with the contrast agent, making it more uniform and preventing rupture of the contrast film. The substance is characterized by almost absolute physicochemical inertness, does not penetrate the tissues of the body and is excreted from it in its original form, without participating in metabolic reactions.


Indications for use according to instructions

Indications for prescribing Sab Simplex to newborns are:

  • flatulence, intense gas formation, bloating, accompanied by abdominal pain and frequent crying of the child;
  • preparation for diagnostic procedures related to the study of the gastrointestinal tract (ultrasound, radiography, esophagogastroduodenoscopy);
  • acute poisoning with powders and other detergents, including surfactants, if they are accidentally ingested.
  • if a newborn is diagnosed with obstructive gastrointestinal diseases;
  • intestinal obstruction or individual sensitivity to simethicone or any other compound included in the drug.

How to properly give Sab Simplex to breastfed and bottle-fed women

Shake the Sab Simplex bottle thoroughly before use. To do this, you should quickly turn it upside down and tap the bottom well: the suspension will begin to actively flow into the pipette.

For colic and severe gas formation, it is recommended to give newborns and infants 0.6 ml (15 drops) of the suspension at each feeding. If the baby is fed breast milk, the medicine is diluted in a small amount of water and given immediately before application. Sub Simplex is highly compatible and mixes well with any liquid, including water, milk and formula. Therefore, for “artificial” babies it is simply added to a bottle with food. For maximum effectiveness, the drug should be ingested every 4-6 hours.

According to the instructions for use, it is possible to give Sab Simplex to a breastfed newborn. For a child who is often breastfed, experts recommend reducing the dose to 10 drops and giving them every 3 hours. For preventive purposes, Sab Simplex is used in a dosage of 6 drops 2 times a day. If the baby suffers greatly from colic, you can give additional medicine before bedtime. To select the optimal treatment regimen for each specific case, it is worth contacting a specialist. The drug is designed for use as part of a long course of treatment.

The first time after starting to take the drug, it is necessary to carefully monitor the newborn, since allergic reactions may develop. There have been no cases of overdose of Sub Simplex.

Its use also has its own characteristics for other indications, in addition to digestive disorders, in newborns:

  1. Preparing for a gastrointestinal examination. When preparing for x-rays, remove the pipette from the bottle and give the baby 3 teaspoons (15 ml) of the drug in the evening the day before the examination. Preparation for an ultrasound requires taking 3 teaspoons of the product in the evening the day before the examination and the same amount 3 hours before the diagnostic procedure. If there is a need for endoscopy, immediately before it, give 2.5–5 ml of suspension (0.5–1 teaspoon). It is also possible to administer a few milliliters of the drug during the procedure directly through the endoscope.
  2. Surfactant poisoning. For poisoning with detergents, the recommended dose is 5 ml (1 teaspoon).

Important! When prescribing laxatives based on lactulose (for example, Duphalac), which provoke increased gas formation, they must be combined with Sab Simplex.

The drug should be stored in a dark place at a temperature not exceeding +25 °C. The medicine remains valid for 3 years, after which it is better not to use it.

Video Sub Simplex for colic

Analogues

The drug has several very popular analogues and sometimes it is difficult for a mother to decide which drug is best to choose in the fight against colic. Let's try to compare Sab Simplex and three other common products.

  1. or Sub Simplex? It is worth considering that 1 ml of Sab Simplex suspension contains 69.19 mg of simethicone, which is higher than in Espumisan L, but less than in Espumisan Baby. The most important advantage of Sub Simplex when choosing between two products is the price, which is higher than Espumisan.
  2. or Sub Simplex? Bobotik, like Sub Simplex, contains simethicone. The dosage is very similar, but doctors do not recommend using Bobotik more than 4 times a day. At the same time, Sub Simplex can be given during each feeding. As for the price of these two products, it is approximately the same.
  3. or Sub Simplex? Unlike Sub Simplex, its main component is a mixture of plant essential oils, which has anti-inflammatory, sedative and analgesic effects. If a child has severe colic, the drugs will complement each other well, but Baby Calm alone will most likely not cope.

The problem of infant colic is familiar to every young mother. This is especially true for babies who are bottle-fed. The child cries and kicks his legs, and the mother’s heart breaks. She frantically searches for how to alleviate the baby’s suffering. To avoid bloating, try using special medications - for example, Sub Simplex drops for newborns.

Sub Simplex drops from a young mother’s medicine cabinet.

Why does a baby experience discomfort?

The newborn’s digestive system is just adapting to the “new life.” That’s why it doesn’t work quite the same way as in adults. Half of the food is not broken down, remaining inside and starting to ferment. The fermentation process causes the formation of gas bubbles.

Formula-fed babies are especially susceptible to gas accumulation. In addition to the bubbles formed inside, portions of air from outside also enter them. It may accumulate in mixtures or be ingested with food.

In breastfed babies, bloating and colic occur due to:

  • improper latching on the breast or the baby crying during feeding - along with a portion of milk, the child also receives a portion of air;
  • consumption by a nursing mother of foods that cause bloating and fermentation in the child’s stomach (legumes, baked goods, fast food, carbonated drinks, etc.).

Whatever the reason for the trouble, Sab Simplex will help the baby.

I took the bunny drops and fell asleep with the bunny.

When to use Sab

The use of the drug is possible from the first days of the baby’s life, whereas for some medications that have a similar effect, for example, Bobotik, the instructions for use indicate not to give it to children under 1 month of age.

In any case, you should consult your pediatrician before use. . Therefore, a specialist must determine how to treat them.

How and what does Sub Simplex work for?

When gas accumulates excessively, it presses on the intestinal walls, causing pain. It is on gas bubbles that Sab acts.

Simethicone, which is part of the composition, destroys the film around gas bubbles. The released air can already be absorbed into the intestinal walls or exit naturally. In this case, the pressure on the intestinal walls stops along with the pain.

Bottom line

Sub Simplex drops are suitable for a baby from the first days of life until the end of the normalization of digestive processes. It can be used both for the treatment of bloating and for prevention. Currently, it is one of the most effective and safest colic medications for newborns.

Tatyana Koshkina

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