Spazmalgon - instructions for use. What is included in spazmalgon Spazmalgon tablets instructions for use

The combined composition of the drug, including a non-steroidal anti-inflammatory drug, an antispasmodic and an M-anticholinergic blocker, is Spazmalgon. Instructions for use indicate that tablets and injections in injection ampoules effectively relieve cramps and pain symptoms, including during menstruation.

Release form and composition

Spazmalgon is available in the form of tablets for oral administration and solution for injection.

The solution for injection is available in dark glass ampoules of 2 ml and 5 ml. The ampoules are placed in plastic pallets of 10 pieces in a cardboard box with attached instructions. A 2 ml ampoule contains:

Metamizole sodium - 1 g (2.5 g in a 5 ml ampoule);
Fenpivirinium bromide – 40 mcg (100 mcg in 5 ml);
Pitophenone hydrochloride – 4 mg (10 mg in 5 ml).

As an excipient - sterile water for injection.

The tablets are round, white, scored on one side, available in blisters of 10 pieces, 1-5 blisters in a cardboard box with attached instructions.

Each tablet of the drug contains 500 mg of metamizole sodium, 5 mg of pitofen hydrochloride, 100 mcg of fenpiverinium bromide, as well as a number of auxiliary components: wheat starch, gelatin, magnesium stearate, lactose monohydrate.

Indications for use

What does Spazmalgon help with? Tablets and injections have extensive indications due to their unique composition. Spazmalgon tablets are used for the symptomatic treatment of mild or moderate pain, in particular for pathologies:

dyskinesia of the gallbladder;
urinary system with pain and disturbances in the urination process, including inflammatory diseases and urolithiasis;
for pain syndrome accompanying dysmenorrhea, as well as for pathology of the musculoskeletal system;
cholelithiasis;
for intestinal and stomach colic, as well as other gastrointestinal pathologies accompanied by spasm of smooth muscle cells.

Indications for the use of Spazmalgon in injection form are relief of high-intensity pain syndrome in renal colic and other pathologies of the intravenous syndrome, postcholecystectomy syndrome, hepatic colic and other diseases of the abdominal cavity and pelvis.

Instructions for use

Taken orally:

adults and adolescents over 15 years of age: 1-2 tablets 2-3 times a day, without chewing, with a small amount of liquid;
children 12-14 years old: single dose - 1 tablet, maximum daily dose - 6 tablets (1.5 tablets 4 times a day);
8-11 years - 0.5 tablets, maximum daily dose - 4 tablets (1 tablet 4 times a day), 5-7 years - 0.5 tablets, maximum daily dose - 2 tablets (0.5 tablets 4 times a day).

Ampoules

For adults, the drug is administered intramuscularly, 2-5 ml of solution for 2-3 days. The duration of treatment is determined depending on the clinical symptoms and etiopathogenesis of the disease, but should not exceed 5 days. The maximum daily dose should not exceed 10 ml (corresponding to 5 g of metamizole sodium).

If there is no therapeutic effect, use of the drug should be discontinued; if the effect is good or satisfactory, proceed to oral or rectal use. Before administering the injection solution, it should be warmed in your hands.

pharmachologic effect

Spasmalgon is a combined anti-inflammatory, analgesic, antipyretic and antispasmodic drug. The mechanism of action of this drug is determined by the properties of the substances included in the composition.

Pitophenone hydrochloride is a myotropic antispasmodic that has a direct effect on the smooth muscles of internal organs, causing it to relax. Metamizole is an NSAID that inhibits cyclooxygenase, as well as inhibits the synthesis of prostacyclin, thromboxane and prostaglandins.

Spazmalgon also contains a substance such as fenpiverinium bromide. It has an anticholinergic effect and has a relaxing effect on smooth muscles. The combination of these three components in Spazmalgon leads to an increase in their pharmacological properties.

Contraindications

granulocytopenia, megacolon;
angle-closure glaucoma;
prostatic hyperplasia with urinary retention;
pregnancy, breastfeeding period;
tachyarrhythmia;
chronic heart failure (stage of decompensation);
serious disturbances in the functioning of the kidneys and liver;
allergy to the components of the drug, pyrazolone derivatives;
stable, unstable angina;
inhibition of bone marrow hematopoiesis.

The drug is contraindicated for use in children under 6 years of age. Spasmalgon is prescribed with caution for diseases of the renal and hepatic systems, low blood pressure (systolic reading below 100 mm Hg), a contraindication is a tendency to bronchospasm.

Side effects

Spasmalgon and drug analogues can cause a number of side effects:

difficulty urinating;
nausea, vomiting;
leukopenia, anemia;
increased irritability;
allergic reactions (itching, urticaria, Lyell's syndrome, toxic epidermal necrolysis);
headache;
acceleration of heart rate, agranulocytosis;
exacerbation of gastritis and peptic ulcers;
malaise, dry mouth;
increased blood pressure.

If the above-described effects occur when using Spazmalgon or analogues, be sure to contact a medical facility.

Children, pregnancy and breastfeeding

Is it possible to drink Spazmalgon during pregnancy? The drug is contraindicated during this period of life due to a lack of clinical studies. The medicine is also not recommended for use during breastfeeding.

The drug is contraindicated in children under 6 years of age. For children over six years of age, the drug is used according to the recommended dosage regimen.

special instructions

When using the drug for more than 5 days, tests should be taken to monitor the levels of platelets and leukocytes, as well as the activity of liver transminases. If thrombocytopenia or agranulocytosis is detected, treatment with Spazmalgon should be stopped immediately.

During drug therapy, it is prohibited to drink alcoholic beverages, as this increases the risk of toxic damage to the liver and kidneys.

During the use of Spazmalgon, patients may experience dizziness, decreased blood pressure, and drowsiness. In view of these data, drug therapy is not recommended to be combined with driving a car or operating complex equipment that requires increased concentration.

Does the drug increase or decrease blood pressure?

The medicine is not used to stabilize blood pressure, however, when using the medicine, spasms of blood vessels are relieved, which may result in a decrease in blood pressure.

Drug interactions

Tranquilizers and sedatives increase the severity of the analgesic effect. Spasmalgon and non-narcotic analgesics, when taken simultaneously, can lead to increased toxic effects of the drugs.

The simultaneous use of cyclosporine and spasmalgon reduces the concentration of the former in the blood. Inducers of microsomal liver enzymes reduce the effectiveness of metamizole. Spasmalgon enhances the effect of ethanol.

Concomitant use with phenothiazine derivatives increases body temperature. Allopurinol, COCs, tricyclic antidepressants disrupt the metabolism of metamizole in the liver, resulting in increased toxicity.

Cytostatics and thiamazole increase the risk of developing leukopenia. The effectiveness of the drug is increased by H2-histamine receptor blockers, codeine, propranolol.

Analogues of the drug Spazmalgon

Analogues are determined by structure:

I took it.
Plenalgin.
Maxigan.
Spasmoblock.
Renalgan.
Bralangin.
Spasmalin.
Baralgetas.
Revalgin.

Vacation conditions and price

The average cost of Spazmalgon (tablets No. 10) in Moscow is 136 rubles. The drug is approved for over-the-counter dispensing from pharmacies.

The expiration date of the drug is indicated on the packaging. The injection solution must be stored in a cool, dark place for no more than 2 years. If the consistency of the solution changes, sediment or suspensions form in the ampoule, the drug cannot be used.

The tablets can be stored at room temperature for 3 years from the date of manufacture.

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Spasmalgon– three-component potent

anesthetic And

antispasmodic drug. The combination of the main components of the drug - fenpiverinium bromide, metamizole sodium and pitofenone hydrochloride ensures mutual enhancement of their pharmacological action and achievement of quick results.

Phenpiverinium bromide belongs to the group of M-anticholinergics, and its main effects are:

dilation of the pupils of the eyes;
increased intraocular pressure;
increased heart rate;
decreased blood pressure;
decreased tone of smooth muscles of the bronchi, gastrointestinal tract, bladder and uterus;
decreased secretory activity of the bronchial, digestive and sweat glands.

Metamizole sodium has a rapid and pronounced analgesic, anti-inflammatory and antipyretic effect.

Pitophenone hydrochloride causes relaxation of the smooth muscles of internal organs - the gastrointestinal tract, respiratory and genitourinary systems, as well as blood vessels. The effect of pitofenone is greatly enhanced by the presence of fenpiverinium bromide.

Accordingly, the combination of these three components provides relief from a painful attack within 15-40 minutes (depending on the route of administration). The therapeutic maximum occurs on average an hour and a half after using the drug. Subsequently, the analgesic effect slowly decreases and completely disappears after 6-10 hours. The duration and strength of action of Spasmalgon largely depends on the condition of the liver and the individual sensitivity of the patient.

Release forms

The drug Spazmalgon is available in tablets and solutions for intravenous and intramuscular administration.

Tablets are available in blisters of 10, 20 and 50 pieces, packed in a cardboard box. Ampoules can be 2 ml and 5 ml, each box contains 5 or 10 ampoules.

Instructions for use of SpazmalgonIndications for use

Spazmalgon has a wide range of applications; it is often used in

gynecology

Gastroenterology,

nephrology

to relieve pain and spastic attacks in internal organs.

Indications for the use of Spasmalgon may be the following conditions or diseases:

headache, migraine-like conditions;
toothache and pain after dental treatment;
spasmodic pain in the stomach and intestines;
spasms of smooth muscles of the bladder and ureters;
urolithiasis (with renal colic);
hepatic colic due to cholelithiasis;
biliary dyskinesia;
pain after gallbladder removal;
menstrual pain;
neuralgia, pain in joints, muscles.

Spazmalgon can also be used as part of complex treatment after various abdominal surgical interventions and invasive diagnostic procedures.

Tablet forms of the drug are most effective for mild to moderate pain. Injection Spazmalgon is preferably used for moderate to severe pain.

Contraindications

Spazmalgon has a fairly large list of contraindications. Hypersensitivity to any of the main active ingredients of Spazmalgon is also a contraindication for its use.

Other contraindications include:

suspicion of acute surgical pathology requiring immediate surgical treatment;
inhibition of the hematopoietic system - aplastic anemia, agranulocytosis, leukopenia;
severe disorders in the liver and biliary tract;
liver and kidney failure in decompensated form;
acute hepatic porphyria;
atony (decreased tone) of the gallbladder and/or bladder;
intestinal obstruction;
megacolon (enlargement of the colon);
arterial hypotension, tendency to faint;
state of collapse;
tachycardia in combination with arrhythmia;
closed-angle form of glaucoma;
prostate adenoma in combination with urination problems;
pregnancy (first and last trimester) and lactation period;
infancy (up to 3 months) or body weight less than 5 kg - for intravenous administration, age up to 5 years - for tablets.

With great caution, the drug is prescribed to people suffering from hay fever, bronchial asthma and other allergic diseases of the respiratory tract, because their condition may worsen.
Side effects

When using Spazmalgon, the following side effects are possible:

dyspepsia – nausea, pain in the stomach, vomiting, dry mouth;
exacerbation of diseases of the gastrointestinal tract - peptic ulcer, gastritis, enterocolitis, etc.;
urticaria, angioedema, in rare cases - anaphylactic shock;
malignant exudative erythema, toxic epidermal necrolysis;
increased blood pressure, arrhythmia, tachycardia;
headache, dizziness, weakness, irritability, blurred vision;
decrease or increase in urine output, change in urine color (bright red color - has no clinical significance), acute interstitial nephritis, acute renal failure;
changes in blood count - agranulocytosis, leukopenia, anemia, thrombocytopenia.

As a rule, side effects occur with long-term use or with intravenous administration of the drug. Side effects rarely occur from taking tablet forms of Spazmalgon in a therapeutic dosage.

How to take Spazmalgon?

To avoid irritation of the mucous membrane of the gastrointestinal tract, Spazmalgon is taken only after meals, and the tablet must be washed down with a sufficient amount

clean water

Intravenous and intramuscular injections of Spazmalgon are given regardless of food intake. If the drug is administered into a vein, the rate of administration should not exceed 1 ml per minute, and the patient should be in a supine position.

For children under 15 years of age, intramuscular administration of the drug is preferable. You cannot administer a cold solution; before administration, the ampoule should be warmed in your hand.

Spazmalgon dosage

For tablet forms: A single dose for adults and children over 15 years of age is 1-2 tablets. It is allowed to use the drug 2-3 times during the day, but the maximum number of tablets per day should not exceed 6 pieces.

Parenteral administration of the drug:

Spazmalgon can be administered intravenously to adults and children over 15 years of age for moderate to severe pain. A single dose is 2 ml, the drug must be administered very slowly. Repeated administration is allowed after 6-8 hours.
From 2 to 5 ml can be administered intramuscularly at a time; injections can be repeated 2-3 times during the day (every 8 hours).

Spazmalgon: instructions for use - video
Spasmalgon for children

Spazmalgon can be given to children in tablets (except for children under 5 years old), and also, if necessary, used in the form of IV or IM injections (children over 3 months old).

Tablet Spazmalgon:

A single dose for children 12-14 years old is 1 tablet, the daily dose is 3-4 tablets, the maximum daily dose is 6 tablets.
Children 8-11 years old are recommended to take Spazmalgon 0.5 tablets at a time, 4 tablets per day are allowed.
Children 5-7 years old should take the drug 0.5 tablets no more than 2 times a day. The maximum daily dose for this category is 2 tablets, the dose is divided into 4 doses.

Injectable forms of the drug:

For children from 3 to 11 months or weighing from 5 to 8 kg, the drug is administered only intramuscularly, no more than 0.1-0.2 ml;
Children aged 1-2 years or weighing 9-15 kg are allowed IV administration - no more than 0.2 ml or IM 0.2-0.3 ml;
At 3-4 years of age or with a weight of 16 to 23 kg, the drug is administered intravenously up to 0.3 ml or intramuscularly up to 0.4 ml;
At 5-7 years old (weight from 24 to 30 kg), up to 0.4 ml can be administered intravenously at a time, intramuscularly - no more than 0.5 ml;
Children 8-12 years old or weighing from 31 to 45 kg IV are allowed to administer 0.6 ml or 0.7 ml IM at a time;
At 12-15 years of age, a single dose of the drug for both IV and IM is up to 1 ml.

The duration of the course of treatment should not exceed 3-5 days. If there is no therapeutic effect, the drug should be discontinued.
Spasmalgon during pregnancy and lactation

In the first and third trimester

pregnancy

taking Spazmalgon is contraindicated, because this drug may cause severe birth defects (

heartlungs

Eye, etc.). In the last trimester of pregnancy, Spazmalgon can cause

uterine bleeding miscarriage

Weakening of labor.

In the second trimester of pregnancy, it is also better for a woman to refrain from taking Spazmalgon, because its effect on the fetus in this period has not been sufficiently studied. If necessary, the doctor will recommend a safer drug to the pregnant woman.

If treatment with Spazmalgon is required during breastfeeding, then breastfeeding should be avoided, because the drug easily passes into breast milk. Breastfeeding can be resumed 48 hours after the last use of the drug.

What does Spazmalgon help with?

Spasmalgon has a wide spectrum of action and can be used for various pains associated with spasm or increased tone of the smooth muscles of organs or blood vessels. Below are specific cases of using the drug.

For headaches

Spasmalgon for headaches can be used only in cases where there is complete confidence that this condition is not caused by increased

intracranial pressure

or cerebrovascular accident. In other cases, Spazmalgon is taken no more than 1 tablet at a time. The drug may be repeated at regular intervals per day, but not more than 4 tablets per day.

For migraines, you can also drink Spazmalgon. In this case, it is advisable to take it before the onset of the attack, at the warning stage. Depending on individual sensitivity, 1-2 Spazmalgon tablets taken at a time, or intramuscular injection of 2 ml of the drug, help relieve vascular spasm. If the migraine already has developed symptoms, then it will not be possible to influence the headache with the help of Spasmalgon.

However, it should be remembered that with frequent or long-term use of combined drugs, which is Spazmalgon, analgesic dependence and addiction to the drug develops.

More about headaches

For toothache For mild or moderate toothache, you can take Spazmalgon in tablet form. A single dose can be 1-2 tablets. No more than 6 tablets are allowed per day. However, it should be remembered that painkillers taken before a visit to the dentist significantly reduce the activity of dental anesthesia. Therefore, your dentist should be warned that you took painkillers, and should also tell him the amount.

When using Spazmalgon after dental treatment, the drug is taken 1 tablet no more than 2-3 times a day. The course of treatment is no more than 2-3 days. If the pain persists for a longer period, you should visit the dentist again to find out the cause of the pain.

More about toothache

For pain during menstruation If menstruation is accompanied by algodismenorrhea (pain caused by increased tone of the muscles of the uterus or inflammatory processes in the genital organs) or there is premenstrual syndrome, Spazmalgon can have a fairly quick effect. In this case, it is recommended to take 1 tablet 2 times a day. In case of intense pain, it is allowed to increase the daily dose to 6 tablets, or administer the drug intravenously in an amount of 2 ml. If repeated administration is necessary, this should be done no earlier than 6 hours after the first injection. The duration of taking the drug is no more than 3-5 days.

During menstruation

Algomenorrhea can often accompany menstruation. These are pains caused by increased muscle tone of the uterus or inflammation in it and other genital organs. In this case, spasmalgon has a quick effect and can eliminate pain due to premenstrual syndrome. According to the instructions, the medicine is taken one tablet twice a day. For very severe attacks, you can increase the dose to six tablets or administer 2 ml of the drug intramuscularly at intervals of six hours. The course of treatment should not last more than 3-5 days.

For headaches

If the patient or doctor is sure that the headache is not caused by increased intracranial pressure or cerebral circulatory problems, then Spazmalgon can be taken as a single tablet. It is permissible to use no more than four tablets per day. The drug can be taken at the stage of precursors of migraine symptoms - before the onset of an attack. Taking 1-2 tablets or 2 ml intramuscular injections will help relieve vascular spasm.

For toothache

For moderately intense toothache, take Spazmalgon tablets in the amount of 1-2 pieces at a time. The maximum daily dose is six tablets. Before going to the dentist, it is better not to use the drug, so as not to reduce the activity of dental anesthesia. After dental treatment, the medicine is taken one tablet 2-3 times a day for a course of 2-3 days.

Directions for use and dosage

The instructions for each release form of Spazmalgon indicate the method of use and dosage. The tablets are taken orally, the solution is administered parenterally (intravenously or intramuscularly). The duration of the course, regimen and dosage are determined by the doctor based on the patient’s age, type of pain syndrome, and individual characteristics.

Spazmalgon tablets

According to the instructions for use, children over 15 years of age and adults take 1-2 tablets 2-3 times a day after meals. You are allowed to take a maximum of six tablets per day, and the maximum course lasts five days. Children 6-8 years old should take 0.5 tablets, 9-12 years old – 3/4 tablets, 13-15 years old – 1 tablet. 2-3 times/day, unless otherwise prescribed by your doctor. Long-term use of the drug threatens the body’s adaptation to the action of the active substances and a gradual weakening of the effect.

Spasmalgon in ampoules

For adults and adolescents over 15 years of age, the injection solution is administered slowly intravenously in 1 ml doses over a minute with a dose of 2 ml. The injection can be repeated after 6-8 hours. According to the instructions, 2-5 ml of solution is administered intramuscularly up to three times a day with a maximum daily dose of 10 ml (5 g of metamizole sodium). Treatment lasts up to five days. Before administration, the solution is warmed in the hand. Dosages for children depend on age, are equal to 0.1-1 ml and differ in increments of 0.1 ml for every two years. Up to three months it is administered only intramuscularly, after which it can also be administered intravenously.

special instructions

In the instructions for use of the drug, it is useful to study the special instructions section. Some excerpts from there:

taking Spazmalgon for more than a week requires monitoring of peripheral blood and liver function; if agranulocytosis or thrombocytopenia is suspected, treatment is stopped;
the drug affects the speed of mental reactions, reducing it and concentration, therefore, during therapy it is not recommended to drive vehicles and dangerous mechanisms;
parenteral administration is used if it is impossible to take tablets orally or if absorption from the gastrointestinal tract is impaired;
intravenous injections are given slowly, in a lying position;
long needles are used for intramuscular injection;
During therapy, urine may become stained.

During pregnancy

Spasmalgon is contraindicated during lactation and pregnancy, especially in the first trimester and the last six weeks of pregnancy. If the doctor determines the potential benefit of the drug is higher than the expected risk to the fetus, the drug will be prescribed, but with constant monitoring. If treatment with Spasmalgon is necessary during breastfeeding, the latter is discontinued.

The tablet form of the medication is contraindicated for children under six years of age; up to 15 years of age, use is possible only as prescribed by a doctor for special indications. Intravenous administration of the drug is prohibited for children under one year old, and intramuscular administration - up to three months or with a body weight of less than five kg. Children's dosage differs from adult dosage from 50 to 75%; after 15 years, adolescents can take an equal dose to adults.

Interaction with alcohol

During treatment with Spazmalgon, it is forbidden to take alcohol and ethanol-containing drinks or medications, because the active substances of the drug enhance the toxic effect of ethyl alcohol. This threatens a large load on the liver, symptoms of overdose and poisoning. During the entire course of taking the medication, you should follow the “prohibition law”.

Drug interactions

The instructions for use of Spazmalgon indicate the presence of drug interactions between the drug and other medications:

tricyclic antidepressants increase the toxicity of the drug;
barbiturates, phenylbutazone, inducers of microsomal liver enzymes weaken the effect of metamizole;
Spazmalgon reduces the level of cyclosporine in the blood;
sedatives, codeine, histamine receptor blockers and tranquilizers enhance the effect of the drug;
use a combination of Spasmalgon and cytostatics, Thiamazole with caution due to the development of leukopenia;
histamine blockers, butyrophenones, phenothiazines, amantadines and quinidines enhance the anticholinergic effect of the drug;
Chlorpromazine and phenothiazine derivatives may cause severe hypothermia;
combination with radiocontrast agents, colloidal blood substitutes, and Penicillin is prohibited;
Metamizole sodium increases the effect of indirect anticoagulants, glucocorticoids, Indomethacin.

Side effects and overdose

The use of the drug may result in the following possible side effects indicated in the instructions:

burning sensation in the stomach, dry mouth;
dizziness, decreased sweating;
difficulty urinating, blurred vision;
decreased blood pressure, tachycardia, cyanosis;
renal dysfunction, nephritis;
urticaria, allergic reactions;
erythema, necrolysis;
Lyell's syndrome;
Stevens-Johnson syndrome.

Symptoms of an overdose of Spazmalgon include vomiting, severe dry mouth, decreased sweating, and blurred vision. The patient may experience a decrease in blood pressure, a runny nose, confusion, and convulsions. According to the instructions, treatment is gastric lavage with the administration of activated charcoal and symptomatic therapy.

Contraindications

If you have the following contraindications specified in the instructions for use, you cannot use Spazmalgon:

hypersensitivity to components derived from pyrazolone, butadiene, tribuzone;
disorders of bone marrow hematopoiesis;
angina pectoris;
chronic heart failure;
liver and kidney dysfunction;
granulocytopenia;
with caution if you are sensitive to non-steroidal anti-inflammatory drugs and non-narcotic analgesics.

Terms of sale and storage

The drug is available without a prescription and is stored in a dry place, protected from children, at temperatures up to 25 degrees for two years.

Direct (similar in active substances composition) and indirect (similar in therapeutic effect) analogues of Spazmalgon, produced by Russian and foreign pharmaceutical factories, are the following drugs in the form of tablets and solution:

pills: Took, Spazgan, Spasmoblock, Spazmalin;
solution: Spazgan, Revalgin, Bralangin, Bral.

You can buy Spazmalgon in pharmacies or online pharmacies at a cost that depends on the chosen form of release and the company’s trade markup. Approximate prices for medicine in Moscow and St. Petersburg:

Mikhail, 37 years old

Last month I had a bad toothache, and my dentist was on vacation and couldn’t see me. To relieve pain before his arrival, I bought Spazmalgon. I liked that the pills worked quickly, the tooth stopped aching. I used the medicine for five days and then my doctor came back and saw me. I will keep this wonderfully working drug in mind.

Sofia, 29 years old

I always take Spazmalgon during the first days of my period - my stomach hurts very badly, and only this drug saves me. Once again I went to the pharmacy and didn’t find it, so I had to ask the pharmacist to give me an analogue of Spazmalgon. She sold me No-shpa, which, according to reviews, does not work well. I'll have to look for my favorite remedy.

Ivan, 32 years old

I work a lot, so I often suffer from headaches. I read from reviews on the Internet that Spazmalgon quickly relieves spasms and pain syndrome. I bought it at the pharmacy and started taking it almost every day. After a month of constant use, I noticed that the effect was weakening and went to the doctor. He scolded me for taking too often and for a long time and prescribed treatment.

Daria, 31 years old

After the operation, the child’s stitches hurt very much and he cried. The doctors admitted him to the hospital and prescribed drips with the painkiller Spazmalgon. Later I found out that the drug had too many side effects, but everything worked out for my son. Next time, before treatment, I will carefully study the prescribed medications.

Clinical and pharmacological group

Spasmoanalgesic

Release form, composition and packaging

◊ Pills white or almost white, round, flat, with a chamfer and a notch on one side.

Excipients: lactose monohydrate - 10 mg, wheat starch - 85.9 mg, talc - 6 mg, magnesium stearate - 4 mg, gelatin - 4 mg, sodium bicarbonate - 5 mg.

10 pieces. - blisters (1) - cardboard packs.
10 pieces. - blisters (2) - cardboard packs.
10 pieces. - blisters (5) - cardboard packs.

pharmachologic effect

The drug contains: the non-narcotic analgesic metamizole sodium, the myotropic antispasmodic drug pitofenone and the m-anticholinergic drug fenpiverinium bromide.

Metamizole is a pyrazolone derivative. It has analgesic, antipyretic and anti-inflammatory effects. Pitophenone, like papaverine, has a direct myotropic effect on the smooth muscles of internal organs and causes its relaxation. Phenpiverinium due to its m-anticholinergic effect, it has an additional relaxing effect on smooth muscles.

The combination of the three components of the drug leads to pain relief, relaxation of smooth muscles, and a decrease in elevated body temperature.

Indications

Mild or moderate pain syndrome due to spasms of the smooth muscles of internal organs - renal and hepatic colic, spasmodic pain along the intestines, algodismenorrhea. Can be used for short-term symptomatic treatment of joint pain, neuralgia, sciatica, myalgia;

As an adjuvant it can be used to reduce pain after surgical and diagnostic interventions;

If necessary, the drug can be used to reduce elevated body temperature during colds and infectious and inflammatory diseases.

Contraindications

Hypersensitivity to nirazolone derivatives (butadiene, tribuzone), to other components of the drug;

Inhibition of bone marrow hematopoiesis;

Stable and unstable angina;

Chronic heart failure in the stage of decompensation;

Severe liver or kidney dysfunction;

Glucose-6-phosphate dehydrogenase deficiency;

Tachyarrhythmias;

Angle-closure form of glaucoma;

Prostatic hyperplasia with a tendency to urinary retention;

Intestinal obstruction and megalocon;

Granulocytopenia;

Pregnancy (especially the first trimester and the last 6 weeks);

Lactation period;

Children's age up to 6 years.

Carefully and under the supervision of a physician, the drug should be used in patients with impaired liver or kidney function, with a tendency to arterial hypotension (systolic pressure below 100 mmHg), bronchospasm, as well as with increased individual sensitivity to non-steroidal anti-inflammatory drugs or non-narcotic analgesics.

Dosage

Adults and children over 15 years old taken orally (preferably after meals), usually 1-2 tablets 2-3 times a day. The daily dose should not exceed 6 tablets. Duration of administration is no more than 5 days.

Increasing the daily dose of the drug or the duration of treatment is possible only on the recommendation and under the supervision of a physician.

Dosages for children.

In children, the drug is used only as prescribed by a doctor.

Dosage for children 6-8 years old- half a tablet, 9-12 years- three quarters of a tablet, 13-15 years old- one tablet 2-3 times a day. Other dosage regimens are possible only after consultation with a doctor.

Side effects

From the digestive system: burning sensation in the epigastric region, dry mouth.

From the nervous system: headache, dizziness, anticholinergic effects (decreased sweating, accommodation paresis, difficulty urinating).

From the cardiovascular system: decreased blood pressure, tachycardia, cyanosis.

From the urinary system: impaired renal function, oliguria, anuria, proteinuria, interstitial nephritis, red staining of urine.

From the hematopoietic organs: with long-term use - thrombocytopenia, leukopenia, agranulocytosis.

Allergic reactions: urticaria, bronchospastic syndrome, anaphylactic shock, Quincke's edema: erythema multiforme (including Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome).

Overdose

In case of an overdose of the drug, the following may occur: symptoms: vomiting, a feeling of dry mouth, decreased sweating, impaired accommodation, decreased blood pressure, sniffling, confusion, impaired liver and kidney function, convulsions.

Treatment: gastric lavage, administration of activated carbon, symptomatic therapy.

Drug interactions

The simultaneous use of Spazmalgon with other non-narcotic analgesics can lead to mutual enhancement of toxic effects. Tricyclic antidepressants, oral contraceptives, and allopurinol disrupt the metabolism of metamizole in the liver and increase its toxicity. Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the effect of metamizole. Simultaneous use with cyclosporine reduces the level of the latter in the blood. Sedatives and tranquilizers enhance the analgesic effect of Spazmalgon.

When administered together with H1-histamine blockers, butyrophenones, phenothiazines, tricyclic antidepressants, amantadine and quinidine, the m-anticholinergic effect may be enhanced.

Enhances the effects of ethanol. Concomitant use with chloriromazine or other phenothiazine derivatives can lead to the development of severe hyperthermia.

X-ray contrast drugs, colloidal blood substitutes and penicillin should not be used during treatment with drugs containing metamizole sodium.

Metamizole sodium, displacing oral hypoglycemic drugs, indirect anticoagulants, glucocorticoids and indomethacin from protein binding, can increase the severity of their action.

Thiamazole and cytostatics increase the risk of developing leukopenia.

The effect is enhanced by codeine, H2-histamine receptor blockers and propranolol (slows down the inactivation of metamizole sodium).

If it is necessary to use these and other medications simultaneously, you should consult your doctor.

special instructions

With long-term (more than a week) use of the drug, monitoring of the peripheral blood picture (leukocyte content) and the functional state of the liver is necessary. If agranulocytosis is suspected or thrombocytopenia is present, the drug should be discontinued.

During treatment with the drug, you should not drink alcohol.

The use of the drug in nursing mothers requires cessation of breastfeeding.

Impact on the ability to drive vehicles and operate machinery

Pregnancy and lactation

Contraindicated during pregnancy and lactation.

Use in childhood

Contraindicated for children under 6 years of age. In children, the drug is used only as prescribed by a doctor.

For impaired renal function

Contraindicated in cases of severe renal impairment.

For liver dysfunction

Contraindicated in cases of severe liver dysfunction.

Conditions for dispensing from pharmacies

Over the counter.

Storage conditions and periods

In a dry place, protected from light, at a temperature not exceeding 25°C. Keep out of the reach of children! Shelf life - 2 years.

The description of the drug SPAZMALGON is based on the officially approved instructions for use and approved by the manufacturer.

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What does Spazmalgon help with? "Spazmalgon" (tablets, injections): instructions, use, reviews

More and more often, recently, people have to resort to taking various medications. So, some drugs save you from viruses and bacteria, others are an excellent painkiller. This article will tell you about what Spazmalgon helps with. It is also worth saying a few words about the reviews that the drug has and the method of its use. You will find out in what forms the medicine “Spazmalgon” is produced.

Composition of the drug

The medicine has a special composition. It contains very strong components that quickly begin to act during treatment. This product contains the following substances:

sodium metamizole in the amount of 500 milligrams;
pitofenone hydrochloride in an amount of 2 to 5 milligrams (depending on the form of release);
fenpiverinium bromide - from 20 mcg (depending on the form of the medicine).

Who is the drug prescribed for?

The drug in tablet form is prescribed to patients who have no contraindications to taking this medication. The only exception is children under 15 years of age. In some cases, the medicine can be prescribed to children over 6 years old, but the recommendation must be given by a specialist.

The drug "Spazmalgon" (injections) can be used from the age of three months. In this case, it is necessary to select an individual dosage, taking into account the course of the disease and the weight of the baby. The medicine "Spazmalgon" in ampoules can also be prescribed to adults who have no contraindications to the use of the drug.

Who should refrain from using the medicine?

If the patient has problems with the kidneys and liver, as well as tumors of the thyroid and prostate glands, then this remedy should absolutely not be used. It is also worth choosing an alternative to the drug "Spazmalgon" (analogues) for women in early pregnancy or one month before giving birth.

The drug is not prescribed to babies under three months of age. Also, tablets are not recommended for children under six years of age.

What does Spazmalgon help with?

This drug is a highly effective new generation drug. It perfectly reduces temperature, relieves various pain sensations and has an anti-inflammatory effect. The special combination of components included in the composition has an enhanced effect on the body.

Metamizole sodium is a drug that relieves inflammation and inhibits the synthesis of prostaglandins. Pitophenone hydrochloride affects the smooth muscles of the whole body, relieving spasms and relaxing them. Fenpiverinium bromide has an additional analgesic effect, helping the previous component work. The drug is prescribed to eliminate various pathologies. Let's take a closer look at what Spazmalgon helps with.

For smooth muscle spasms and pain syndrome

The drug perfectly helps with periodic pain in women associated with the characteristics of the menstrual cycle. The product also perfectly eliminates colic of various origins (renal, hepatic, intestinal, and so on).

“Spazmalgon” helps very well against toothache. Also, while taking the drug, the shooting sensations in the head disappear. It is worth noting that such pain can have a different nature (narrowing or dilation of blood vessels, spasm of nerve endings, and so on). The drug can even cope with migraines. However, in this case it must be taken as early as possible.

For neurological diseases

The drug effectively copes with a variety of unpleasant sensations caused by neurological problems. These include the following: pinched nerve, atralgia, myalgia, and so on.

It is worth noting that in these cases the greatest effect can be achieved in the liquid form of the drug (with intravenous or intramuscular administration). However, tablets also have a positive effect in treatment.

After various interventions

The drug perfectly relieves pain after surgery. In this case, it doesn’t matter what exactly causes discomfort. The product can relieve muscle spasms and pain in the joint, turn off the sensitivity of the skin and “de-energize” the nerve endings.

Often after operations, the drug is prescribed for preventive purposes. In this case, all forms of this drug are used. In some cases, the medicine is used as a premedication (before surgery).

As an antipyretic and anti-inflammatory agent

What else does Spazmalgon help with? As you already know, the drug has the ability to relieve fever and inflammation in various human organs and systems. Thus, the drug is prescribed to relieve influenza and treat colds. The drug perfectly relieves fever and improves the patient's condition.

Most often, capsules are used for oral administration, with the exception of illness in young children.

How to use the product?

You already know that the drug has two release forms. At the same time, the drug "Spazmalgon" is prescribed to children more often for intramuscular or intravenous administration. In each individual case, a separate dosage and duration of treatment are selected.

The tablets are taken after eating food with sufficient water. You can take no more than six capsules per day. In this case, a single dose should not exceed two pills. You can use the medicine only after 15 years.

In some cases, doctors may prescribe this medicine to young children. In this case, the dosage should be as follows. From 6 to 8 years - half a capsule per dose. After 9 years - three quarters of a tablet to take. You can use a repeated dose no more than three times a day.

Injections

This dosage form can be used from three months of a child’s life. The dosages will be as follows. In the first year of life - 0.1 milliliters of the drug. Up to four years - double dose (0.2 ml). After five years -0.4 milliliters once. Children aged 8 years and older are administered 0.5-0.8 milliliters.

Treatment with this remedy should not last more than five days. If the doctor has established his own course of treatment, then it is necessary to monitor the condition of the circulatory system and liver.

Can there be negative reactions to the medicine?

Like any other drug, Spazmalgon has side effects. Among them are the following:

allergies (manifested by urticaria, itching of mucous membranes or anaphylactic shock);
heart reaction (increased heart rate, abnormal blood pressure, dizziness or fainting);
reaction of the circulatory system (observed only with prolonged uncontrolled use of the drug);
reaction of the respiratory system (shortness of breath, bronchospasm).

Can the medicine be used with other drugs?

The product may not be combined with some medications. For example, when used with hormonal contraceptives or certain depressants, the drug has a particularly harmful effect on the condition of the liver and blood.

If you use the drug together with sedatives, you can get a pronounced analgesic effect. In any case, it is better to divide the time of taking different medications so that there is a gap of at least 2-3 hours between them.

When using the medicine, you should refrain from taking antipyretic drugs. Because otherwise, an overdose of the active substance may occur and a negative reaction may occur.

"Spazmalgon": analogues

Currently, manufacturers produce a wide variety of non-steroidal anti-inflammatory drugs. So, among them we can highlight “Nurofen”, “Solpadein”, “Spazgan” and many others.

Some patients try to replace their prescribed medication with a more affordable one. So, the question often arises about what to choose - “Spazmalgon” or “Spazgan”. Doctors strongly do not recommend self-medication and not looking for an alternative to the medicine on your own. Use only the drug prescribed by your doctor.

Price category

The medicine has different release forms and number of doses. So, the manufacturer produces tablets of 20 and 50 pieces per package. A small pack will cost you about 100 rubles. If you need to purchase a large package, then be prepared to pay from 200 to 250 rubles for it.

Injections are available in 2 and 5 milliliters per dose. In this case, you can find 10 ampoules in a pack. A smaller dosage costs from 200 to 250 rubles. Larger volume injections will cost you approximately 350 rubles.

Reviews about the medicine

The drug has mostly positive reviews. However, some patients note that the product has a rather toxic effect on the body. That is why it should not be used on its own for more than five days. Also, negative effects may be observed if the dose of the drug is increased.

People who have used the product say that the most common symptoms of overdose are pain in the stomach and intestines. This applies to the capsule form of release. If a person abuses injections, then fainting, vomiting and diarrhea may occur. Doctors say that treatment should be started immediately.

Summing up and a short conclusion

Now you know what the drug Spazmalgon can help with. Remember that you should not prescribe such a potent medicine yourself. If you need one-time pain relief, you should choose analogues of this drug. Never give the medicine to small children or those people who have contraindications to the use of the medicine. Before use, always read the instructions carefully and follow the advice of your doctor. Only in this case, the benefit from the treatment provided will be significantly greater than the harm received from the drug. Be healthy!

Spazmalgon - what does it help with and how to take it?

There are medications that almost every person has in their home medicine cabinet. These are Activated carbon, Paracetamol, Acetylsalicylic acid, etc. More and more often you can meet people who add Spazmalgon to the list of mandatory medications. This drug is used as an effective pain reliever, which has a rapid effect and several forms of release. Spazmalgon is used both when single attacks of painful sensations occur, and as part of complex treatment of various ailments prescribed by a doctor. Let's consider all aspects of the use of this drug and existing restrictions.

Composition and active ingredient of the drug

The active ingredient of the drug is a substance called metamizole sodium. It is a non-narcotic analgesic and myotropic antispasmodic, has anti-inflammatory, antipyretic properties and the ability to reduce pain. Its content in one tablet is 500 mg. The drug also contains other active ingredients in smaller quantities:

pitofenone - has a direct effect on smooth muscle structures, promoting its relaxation;
fenpiverinium bromide - a substance necessary to enhance the relaxing effect.

The combination of all the described components of the drug allows you to achieve a targeted and pronounced effect; taking the tablets effectively relieves spasms and minimizes pain.

The composition also includes auxiliary components that may affect the ability to take the drug due to the likely development of individual intolerance to at least one of them: lactose, wheat starch, gelatin, talc, magnesium stearate, sodium bicarbonate.

There is also a liquid form - solution for injection (ampoules of 2 and 5 ml). The choice of form is made depending on the intensity of the painful sensations that need to be neutralized.

How long does it take for Spazmalgon to work?

Considering the fact that the drug contains several active substances that complement and support each other’s action, the effect occurs quite quickly. After entering the stomach, the substances are quickly absorbed, and the maximum concentration in the blood mass is reached after a third of an hour. After injection of Spazmalgon, the effect is achieved in just 8-10 minutes.

Indications for use of the drug

Before deciding to use a particular drug, it is important to understand exactly how it works. Some perceive Spazmalgon as a pain reliever, and it really helps with painful sensations, but only of a certain nature. Therefore, the list of indications for which tablets and injections will provide relief is of particular relevance.

Spazmalgon tablets for headaches and migraines

The described drug can provide active relief from painful sensations and severe migraines if such symptoms are provoked by a spasm (sudden changes in pressure, problems with blood vessels, drinking coffee and strong tea in large quantities, fatigue, nervous tension). Discomfort caused by spasm of blood vessels or muscles will be eliminated, as Spazmolgon will relax tense areas. The pills also help with hangovers.

The drug is also used to relieve symptoms of migraines, but the effect will only be if the pill was taken in advance, otherwise the pain relief will be temporary and the discomfort will return after the active substance wears off.

Use for menstrual pain

During menstruation, a substance called prostaglandin begins to actively work in the uterus, which stimulates contractions of the organ to effectively remove the necessary tissues and fluids out. High levels of these substances can provoke too strong contractions - spasms, which will cause severe discomfort, in some cases even pain in the lower abdomen. Not every woman suffers from this, but if discomfort occurs, then it is necessary to deal with it. Spazmalgon will help reduce the increased activity of contractions, but it is worth considering that it cannot be used in case of renal failure and problems associated with hematopoiesis.

For toothache

Considering the specifics of the drug, it is important to find out whether Spazmalgon will help with toothache, because we are talking about bone tissue. First of all, it is worth noting that a tooth can hurt for the following reasons:

there are enamel destructions;
caries has developed to the pulp, which provoked its inflammation;
the inflammatory process has spread not only deep into the tooth, but also to the surrounding tissues, etc.

All of the situations described above are accompanied by pain, most often it is pulsating and shoots sharply. Taking the described drug in this case will help relax the muscle tissue, and painful impulses will not be able to spread, due to which the “lumbago” and pulsation will no longer bother you. Thus, Spazmalgon can be used as an effective remedy for toothache. However, if there is an active inflammatory process in the oral cavity, then there may be no effect from taking the pill at all, and in this case it is better to immediately contact a dentist.

At a temperature

The main active ingredient of the drug, among its properties, has the effect of lowering body temperature. For this reason, tablets and injections can be used when the thermometer is high, if it is caused by colds or infectious-inflammatory causes. In the case where the increase is psychosomatic in nature, the drug is not effective.

For cystitis

The ingredients of the drug include fenpiverinium bromide, which is specifically used for pain syndromes of varying severity that accompany various diseases of the internal organs: biliary colic, chronic colitis, hepatic colic, impaired motility of the biliary tract, etc. Its use will also be effective for inflammation of the bladder (cystitis), including for the temporary treatment of pain due to surgical interventions or diagnostic tests. The effectiveness of the tablets is achieved due to the fact that the relaxing effect will relieve tension from the ureter, thereby minimizing pain.

For abdominal pain

The effectiveness of taking the drug for pain in the elements of the digestive system will be achieved only if the discomfort is provoked by muscle spasms (for example, with intestinal colic or cramping pain in the stomach).

Can I take it during pregnancy and lactation?

The described drug should not be used during pregnancy and breastfeeding. If during breastfeeding there is an urgent need to use Spazmalgon as part of treatment, then feeding should be stopped for a while.

Spazmalgon: increases or decreases blood pressure?

An increase in pressure is a direct consequence of a spasm of the vascular elements, when their lumen narrows and it becomes more difficult for blood to move. Taking into account the peculiarities of the composition of the drug in question, it becomes obvious that its use reduces blood pressure, as vascular spasm is relieved. However, it is worth noting that Spazmalgon is not suitable as a separate drug for stabilizing blood pressure; it can only be used as a last resort, if you need to quickly normalize the situation, and there are no specialized drugs.

Instructions for use of Spazmalgon tablets and injections

Taking the tablet drug without a doctor's prescription can last a maximum of three days. The dosage depends on the patient's age:

an adult can take up to 2 tablets at a time, but no more than 6 tablets during the day;
teenagers (12-16 years old) can take only one tablet at a time, with a maximum of 4 tablets per day;
at the age of 8 to 11 years, one dose should be no more than half a tablet, the daily maximum is 3 pieces;
children from 5 years of age - half at a time, maximum 2 whole tablets throughout the day.

It is worth considering that the interval between doses of the drug should not be less than 4 hours. The tablet should be taken whole, washed down with water, without crushing or chewing.

As for the injection solution, it is administered intramuscularly and for an adult the dosage is from 2 to 5 milliliters a maximum of three times a day. The total daily dose should not exceed 10 ml of the drug. Stop injection therapy if it does not produce results or if there is improvement and you can switch to the tablet form of the drug.

Harm from use and side effects

Harm from using the drug can occur if the rules of administration are ignored or the recommended dosages are exceeded. The manufacturer indicates the following possible side effects:

allergic reactions with skin manifestations;
some discomfort in the stomach;
decreased blood pressure;
heart rhythm disturbance;
vision problems;
a feeling of dryness in the mouth;
in the presence of gastritis - its exacerbation;
urinary retention;
development of renal failure;
with a tendency to bronchospasm, an attack may begin.

In case of an overdose, an extensive allergic reaction, digestive tract disorders, and, in especially severe cases, symptoms of brain damage usually occur. If even minimal side effects occur, you should stop taking the drug and seek medical help.

What are the contraindications?

Taking the drug must be consistent with the contraindications indicated in the instructions, otherwise not only will the desired effect not be achieved, but an unpleasant deterioration may also occur. The following admission restrictions apply:

chronic heart failure;
serious functional disorders of the kidneys and liver;
angle-closure glaucoma;
angina pectoris;
obstruction of the digestive tract;
diseases of the prostate gland with a tendency to urine retention;
children's age (meaning up to 6 years);
presence of alcohol in the body;
in the presence of individual intolerance.

You should approach taking Spazmalgon with some caution if you have any kidney or liver disorders, a tendency to low blood pressure and bronchospasm.

Cheap analogues of the drug

The closest analogues of Spazmalgon in composition are the drugs Baralgetas, Maxigan, Renalgan, Spazmadol, Spazgan, but not all of them can be called cheap. The most affordable product is Renalgan.

Video: all about Spazmalgon tablets

Reviews

Dasha. On the first day of my period I just have terrible pain in the lower abdomen, for a long time I have been saving myself only with Spazmalgon. Half an hour and it becomes much easier.

Renat. Gastritis often suffers from attacks in the off-season. To get rid of the pain, ordinary painkillers are not suitable, I resort to the help of Spasmalgon. It relieves painful spasms well and acts very quickly, which is especially important if you have severe discomfort.

Lisa. In our pharmacies this is the most affordable remedy of this kind, it helps with almost any pain, our family uses it all the time!

Spazmalgon - tablets for headaches: instructions, prices and reviews

It is not advisable to endure a headache. When your head literally “breaks” and the usual remedies (Citramon) no longer help, you can use stronger drugs, for example, take a Spazmalgon tablet. The effect of Spazmalgon on headaches is somewhat similar to that of the long-known “troika”.

Instructions

Metamizole sodium + Pitophenone + fenpiverinium bromide (Spazmalgon) belongs to the group of analgesics.

pharmachologic effect

The components of the drug have a complex effect, relieving pain. Metamozole sodium (an analgesic, known as Analgin) relieves inflammation, reduces fever and blocks pain by reducing the synthesis of prostaglandins. Pitophenone (an antispasmodic) removes muscle vascular tone.

Phenpiverinium bromide (an antispasmodic), reducing the hypertonicity of smooth muscles, blocks pain and has a relaxing effect.

Indications for use

The drug is usually used to relieve pain:

For renal and hepatic colic;
with spastic pain in the intestines;
with painful menstruation;
for arthritis, sciatica, neuralgia.

Mode of application

Children under 6 years of age should not take Spazmalgon. After 6 years, it can only be prescribed by a doctor.

For adults and adolescents over 15 years of age, it is possible to use Spazmalgon no more than 6 tablets per day; it is not advisable to take Spazmalgon for more than 5 days in a row.

It is advisable to take the tablets after meals. It is recommended to take Spazmalgona for headaches once.

Do you know what other medications are available for migraines? Triptans for migraines have also proven successful among those who suffer from excruciating headaches.

You can find out about the causes of headaches with osteochondrosis of the cervical spine here.

Side effects

Taking the drug can sometimes provoke:

Increased heart rate;
Frequent use of the drug leads to decreased immunity.
decrease in pressure;
headache;
pain and burning in the stomach area

Contraindications

The drug has many contraindications and its use is prohibited:

Children under 6 years old;
women during pregnancy and breastfeeding women;
for heart diseases (angina pectoris, heart failure, arrhythmia);
with intestinal obstruction;
with impaired renal function;
with functional disorders in the liver;
at low blood pressure;
for diseases of the prostate gland;
with a tendency to bronchospasms.

Taking the drug may weaken mental and physical reactions. Persons driving vehicles should refrain from using it.

Use during pregnancy

The drug can cause abnormalities in the development of the heart and lungs of the fetus.

In late pregnancy, the drug can lead to both weakening of labor and post-term pregnancy.

Interaction with other drugs

Concomitant use of other medications with Spazmalgon may lead to the following undesirable side effects:

The toxic effect of the drug increases when taken together with contraceptives, other analgesics and antidepressants.
Barbiturates weaken the analgesic effect of Spasmalgon.
The combined use of Spazmalgon with penicillin is undesirable.
It is not recommended to drink alcohol while taking the drug.

Overdose

An overdose of Spazmalgon can provoke: gag reflex, stomach pain, drowsiness, dry mouth, impaired consciousness, convulsions. In such cases, it is urgent to take activated carbon and drink as much drinking water as possible.

In case of intoxication of the body with this drug, you must urgently call a doctor.

Release form

The drug is prepared in the form of tablets and solutions for injection. Packages of Spazmalgon are sold in 20 and 50 tablets.

Storage conditions

Spazmalgon is stored at temperatures up to 25° in a dry place.

Compound

Active components:

Metamizole sodium (500 mg);
pitofenone hydrochloride (5.0 mg);
fenpiverinium bromide (0.1 mg).

The following additives are used: starch, talc, gelatin, lactose, magnesium stearate and sodium bicarbonate.

Additionally

Trade names of the drug:

Spasmalgon;
Spazgan;
Took;
Baralgetas;
Maxigan;
Revalgin;
Spasmalin;
Bralangin.

Where to buy and price

Spazmalgon in tablet form is sold in pharmacies without a prescription. The average price for a package of Spazmalgon is 120 rubles.

The choice of treatment method for cerebral vascular ischemia is a fundamental factor for a favorable outcome of the disease. Stages of development.

Headaches are one of the accompanying symptoms of increased intracranial pressure. The causes of increased intracranial pressure in adults can be found here.

All about the symptoms of dyscirculatory encephalopathy of the brain can be found at the following link:

According to numerous reviews, Spazmalgon helps get rid of the painful condition caused by migraine attacks. By taking one Spazmalgon tablet, the attack can be stopped within 20 minutes.

Spasmalgon is an inexpensive and effective drug that allows you to get rid of headache attacks in cases where other drugs are no longer effective.

Like all chemical drugs, Spazmalgon can lead to a large number of side effects, so you should not get carried away with it.

Remember, when headaches become constant companions in everyday life, urgent consultation with a specialist is necessary.

A video that highlights a brief description of the drug “Spazmalgon”:

What does Spazmalgon help with - how and how long does it take to act?

Spasmalgon is a drug that contains an antispasmodic, an M-anticholinergic blocker and a non-steroidal anti-inflammatory drug. The tablets have a pronounced anti-inflammatory, analgesic, antipyretic effect and are used to quickly eliminate pain, as well as as an antipyretic for ARVI or influenza. Next, we will take a closer look at what Spazmalgon helps with and the features of its use in adults and children.

Indications for use of Spazmalgon

The combined composition of Spazmalgon makes the drug literally universal. In other words, the scope of application of Spazmalgon tablets is very extensive. Thus, taking tablets is indicated in the presence of mild or moderate pain syndrome that occurs against the background of diseases such as:

intestinal and stomach colic, various disorders of the gastrointestinal tract;
diseases of the urinary system accompanied by urination disorders;
dysmenorrhea and diseases of the musculoskeletal system;
dyskinesia of the gallbladder;
cholelithiasis and other ailments accompanied by pain and discomfort.

Spazmolgon (injections) in the form of an injection solution should be used in cases where there is a need to quickly relieve pain due to postcholecystectomy syndrome, hepatic or renal colic and other diseases of the abdominal cavity. The active components of the tablets are removed from the body through the urinary system.

Spasmalgon for headaches

Spasmalgon helps against headaches in cases where the pain syndrome is not a consequence of increased intracranial pressure or cerebrovascular accident. In all other cases, taking the drug is allowed in a dosage of no more than 1 tablet at a time. The instructions for use of Spazmalgon state that the daily dose should not exceed 4 tablets. Taking the drug is also indicated for migraines, but doctors advise drinking the drug before the onset of an attack, at the warning stage. Otherwise, it will not be possible to treat severe headaches with the help of tablets.

For pain during menstruation

Often, menstruation is accompanied by pain in the abdominal area, caused by an increase in the tone of the muscles of the uterus, and inflammatory processes occurring in the genitals. Spasmalgon during menstruation helps to eliminate them quickly and effectively. To relieve discomfort, it is recommended to take 1 tablet 2 times a day. In case of severe pain, it is allowed to increase the dose to 6 pieces per day.

For toothache

Spasmalgon also shows its effectiveness in cases where there is a need to eliminate toothache of mild to moderate intensity. No more than 2 tablets are allowed to be taken at a time. The maximum dose is 6 pieces per day. Remember that Spazmalgon taken before going to the dentist significantly reduces the effectiveness of anesthesia, so warn the doctor in advance. After dental treatment, the drug is taken in a dosage of 1 tablet. no more than 2-3 doses per day. The duration of the course of treatment should be no more than 2-3 days.

For stomach pain

Pain in the stomach and intestinal colic, provoked by spasms of smooth muscles, can be eliminated with the help of Spasmalgon. The antispasmodic effect allows them to be taken in case of discomfort arising from an exacerbation of biliary dyskinesia and urolithiasis.

For cystitis

Spazmalgon contains fenpiverinium bromide, an active substance that helps cope with pain resulting from the development of inflammatory diseases of the urinary tract. When inflammation occurs, the tension in the ureter is weakened, resulting in difficulty urinating. In this situation, the drug relieves pain and discomfort.

Spasmalgon (in Latin - Spasmalgon) is a widely used medication used for many ailments. Its most effective use is for pain caused by spasms of various origins. Like any other remedy, it has a number of indications and contraindications.

Spasmalgon (in Latin - Spasmalgon) is a widely used medication used for many ailments.

Composition and action

One tablet contains metamizole sodium - 0.5 g, pitofenone hydrochloride - 5 mg, fenpiverinium bromide - 100 mcg. Auxiliary components are added to the tablet to give it its shape.

1 ml of injection solution contains 0.5 g of metamizole sodium, 2 mg of pitofenone hydrochloride salt, 0.02 mg of fenpiverinium. Other substances are deionized water and preservatives to ensure sterility.

The active substance of the drug has a strong antispasmodic effect.

Release form

On sale you can find tablets for oral administration and liquid for injections.

Pharmacological properties of Spazmalgon

Chemical properties provide the therapeutic characteristics of the drug.

Pharmacodynamics

It is a combined medication with a strong antispasmodic effect.

Metamizole is a non-steroidal anti-inflammatory substance related to pyrazolone homologues. It has a strong analgesic effect and exhibits an anti-inflammatory effect. The mechanism of activity of the substance is due to the influence of the cyclooxygenase compound. This enzyme disrupts the formation of arachidonic acid.

Metamizole sodium helps reduce the activity of prostaglandins, prostacyclins and thromboxane (active substances that contribute to the development of the inflammatory process in the human body). Deactivates the action of cyclooxygenase-1 and cyclooxygenase-2. As a result of inhibition of the activity of these components, inhibition of the susceptibility of receptors to pain impulses is observed.

A decrease in the synthesis of prostaglandins after the use of Spazmalgon leads to a decrease in the production of active substances within the body, which take part in inflammatory processes.

The antipyretic effect is associated with a decrease in local temperature in the area of inflammation. It also helps reduce pain.

Pitophenone is a homologue of piperidine. Has pronounced antispasmodic activity. Reduces tension and activates relaxation of smooth muscle tissue. Thanks to this, the remedy helps eliminate pain caused by spasms.

Phenpiverinium bromide is a chemical compound from the category of m-anticholinergic blockers. It contains quaternary nitrogen in its structure. Eliminates spasm of the smooth muscle layer of internal organs, reduces the degree of muscle tension, reduces the intensity of intestinal and stomach peristalsis. The substance intensively relaxes the smooth muscles of the organs.

All chemical compounds included in Spazmalgon complement and enhance each other.

Pharmacokinetics

Pharmacokinetic properties are presented based on information for metamizole sodium only. Information on the pharmacokinetics of other drugs is incomplete.

After internal use, metamizole enters the bloodstream in the gastrointestinal tract. Hydrolysis occurs in the intestinal walls with the synthesis of a chemically active breakdown product. Peak concentrations of the metabolite are observed later than 0.5-2 hours after internal use.

Bioavailability after intramuscular administration is approximately 85%. Not administered intravenously. Binds predominantly to plasma proteins. Metabolism occurs in the liver with the formation of active components. A small part is evacuated with the liver. The vast majority of metabolic products are excreted in the urine.

In case of hepatic pathologies, a decrease in the rate of elimination of the drug may be observed. In some people, due to genetic characteristics, drug metabolism parameters may change.

What do they help with?

Tablets or injections are used in the following cases:

Symptomatic treatment of people suffering from pain of varying degrees, including migraine.
Pathologies of the urinary tract, accompanied by pain and inflammation, especially urinary tract infections.
Colic in the tissues of the stomach and intestines, resulting from spasm of their muscles.
Impaired patency of the bile ducts.
Painful sensations resulting from primary or secondary dysmenorrhea.
Diseases of the musculoskeletal system, muscle and joint pain due to osteochondrosis (in this case, the drug is recommended to be used for a short period of time).
Renal colic (intramuscular injections are prescribed to relieve pain, because oral administration is ineffective).
A syndrome that manifests itself in the body after cholecystectomy.
Pathologies of the pelvis, accompanied by inflammation and pain.
After surgical interventions to eliminate pain.

Use of the drug Spazmalgon

The regimen and dosage depend on the dosage form of the drug, the age of the patient and his condition.

Pills

It must be swallowed whole and should not be chewed or crushed. Wash down with the required amount of boiled water. Sometimes the tablet is allowed to be divided according to risk, but in this case you need to drink two whole halves of the medication.

The duration of therapy is determined by the doctor.

Solution

Adults or adolescents are prescribed 2 to 5 cm³ of solution 2 or 3 times over 24 hours. The interval between injections must be maintained at least 6 hours. You should not administer more than 10 cm³ of solution per day. Injections should not be prescribed for more than 3 days in a row unless a specialist decides otherwise. If the dynamics are positive, they switch to using the medication in tablet form.

For pain

The medication is active for pain of any origin. For headaches, toothaches and discomfort in the stomach, take a pill. To relieve pain during menstruation, injection is recommended. Special caution should be exercised when prescribing Spazmalgon for abdominal discomfort: it is dangerous for appendicitis, cholecystitis, pancreatitis and perforated ulcers.

Before or after meals

How long does it take to work?

After use, the tablet begins to act after 20-30 minutes, intramuscular injection - after 5-7 minutes.

How to take Spazmalgon for urolithiasis

With urolithiasis, short-term use of the medicine is possible. Intramuscular injection is most effective. If there is no effect, then you need to inject Promedol, Baralgin.

How long does Spazmalgon last?

The action lasts up to 12 hours.

Contraindications

The drug is prohibited in the following cases:

Hypersensitivity to the components of the drug and similar substances.
Hypersensitivity to pyrazolone analogues and derivatives.
Signs that may indicate the development of surgical pathology in a patient.
Severe dysfunction of the hematopoietic system, including agranulocytosis, decreased leukocytes, anemia of any type.
Severe renal or liver failure, porphyria.
Decreased bladder tone.
Angle-closure glaucoma.
Arrhythmia.
Insufficiency of the enzyme glucose phosphate dehydrogenase in the body.
Obstruction of the digestive tract.
Megacolon.
Collaptoid state.
Prostate adenoma, accompanied by severe urinary disturbances.
Pregnancy, breastfeeding.
The patient's age is up to 15 years.

The drug should be used with caution in the following conditions:

hay fever;
asthma;
runny nose of allergic origin;
reflux and gastroesophageal disease;
open-angle glaucoma;
decreased intestinal tone;
changes in uterine tone;
dysfunctions of the heart and blood vessels.

Side effects

When the medicine is administered, side effects may appear:

Disorders of the digestive tract. Patients experienced pain in the abdomen, nausea, vomiting, and increased formation of gases in the intestines. In patients with chronic diseases of the digestive tract, exacerbations were observed.
Symptoms associated with abnormalities in the circulatory system: increased blood pressure, heart rhythm disturbances.
On the part of hematopoiesis, disturbances in indicators are possible - a decrease in the number of red blood cells and platelets, agranulocytosis, anemia.
The appearance of pain in the head, syncope of varying severity, irritability. Rarely, visual impairment may occur - double vision, blurred objects.
Damage to the urinary system. Difficulty urinating may develop. Often there may be a decrease in urine production or, conversely, an increase in its quantity (polyuria) and frequency of urination (pollakiuria). In rare cases, patients' urine may turn bright red. Patients who take the drug for a long time may suffer from cystitis or kidney problems.
May occur: itching, skin rash, severe urticaria and Steven-Johnson syndrome. It is extremely rare that anaphylactic shock may develop. People prone to bronchospasm and patients suffering from asthma may develop narrowing of the bronchi.

In all cases of side effects, you should immediately stop taking it and consult a doctor. Immediate discontinuation is recommended in case of abnormalities in the functioning of the kidneys, liver and the likelihood of developing hypersensitivity.

Overdose

In case of overdose, there may be an increase in the intensity of undesirable effects, in particular toxic-allergic ones. With a further increase in dosage, the development of dysfunctions in the gastrointestinal tract and central nervous system is observed.

There is no antidote. It is necessary to rinse the stomach and prescribe symptomatic medications. It is necessary to take measures to quickly evacuate the substance from the blood.

special instructions

With prolonged use (more than a week), you need to monitor your blood quality and do an electrocardiogram. It is necessary to take into account the amount of metamizole sodium in other medications taken by the patient.

The medicine can cause red urine. This phenomenon is not associated with hematuria and disappears after discontinuation.

Use during pregnancy and breastfeeding

Today there is no data on how safe the drug is during gestation, in particular in the early stages. Therefore, it is not prescribed to women in the gestational period.

If there is a need to drink or inject medication during breastfeeding, the child is temporarily transferred to formula. Restoration of breastfeeding is allowed after 2 days from the date of cessation of use of the drug.

Use in childhood

Not prescribed for children under 6 years of age. Up to 8 years of age, half a tablet of Spazmalgon is used. Up to 12 years of age, the permissible dosage of the drug is 0.75 tablets. Children over 12 years old are given an adult dosage.

For impaired renal function

In case of renal impairment, caution should be exercised. The elimination of the drug may be delayed in patients with excretion disorders.

For liver dysfunction

In case of inflammatory pathologies of the liver, it is necessary to reduce the dosage to the minimum effective. The medicine should not be used if there is severe liver failure.

Alcohol compatibility

The medicine is incompatible with alcohol. During the treatment period, you should not drink any drinks containing it. Alcoholic drinks cause depression of the central nervous system, sometimes a coma. Should not be used if you have a hangover.

Drug interactions

The following reactions may occur:

When using Spazmalgon, the therapeutic effect of drugs from a number of coumarin anticoagulants is reduced.
Taking Chlorpromazine can contribute to a pronounced drop in body temperature.
The medicine reduces the therapeutic concentration of Cyclosporine.
Metamizole can provoke the appearance of bone marrow dysfunction due to its myelotoxic effect on the body.
Barbiturates and similar medications reduce the effectiveness of Spazmalgon.
Tricyclic antidepressants, Allopurinol, and oral contraceptives enhance the toxic effect of metamizole.
Non-steroidal anti-inflammatory drugs, when used in combination, increase the risk of developing undesirable effects.
An enhanced analgesic effect is possible when prescribed with sedatives and sedatives.
When Spazmalgon is used with quinine-containing drugs, an increase in anticholinergic effect is recorded.

Analogues

Analogues are:

Baralgin;
Nise;
Diclofenac (this medication is much cheaper);
Spazgan;
No-shpa;
Revalgin;
Baralgetas.

Terms and conditions of storage

Suitable for use within 3 years from the date of production.

Conditions for dispensing from pharmacies

Released without presentation of a medical document. Manufacturer: Balkan Pharma, Bulgaria.

Price

The cost of 20 Spazmalgon tablets is about 135 rubles. The cost of 10 ampoules of 2 ml is 600 rubles. The cost of 10 ampoules of 5 ml is 1000 rubles.

Composition of the drug

The medicine has a special composition. It contains very strong components that quickly begin to act during treatment. This product contains the following substances:

sodium metamizole in the amount of 500 milligrams;
pitofenone hydrochloride in an amount of 2 to 5 milligrams (depending on the form of release);
- from 20 mcg (depending on the form of the medicine).

Who is the drug prescribed for?

Who should refrain from using the medicine?

The drug is not prescribed to babies under three months of age. Also, tablets are not recommended for children under six years of age.

What does Spazmalgon help with?

For smooth muscle spasms and pain syndrome

“Spazmalgon” helps very well against toothache. Also, while taking the drug, the shooting sensations in the head disappear. It is worth noting that such pain can have a different nature (narrowing or expansion of nerve endings, and so on). The drug can even cope with migraines. However, in this case it must be taken as early as possible.

For neurological diseases

The drug effectively copes with a variety of unpleasant sensations caused by neurological problems. These include the following: atralgia, myalgia, and so on.

After various interventions

Often after operations, the drug is prescribed for preventive purposes. In this case, all forms of this drug are used. In some cases, the medicine is used as a premedication (before surgery).

As an antipyretic and anti-inflammatory agent

Most often, capsules are used for oral administration, with the exception of illness in young children.

How to use the product?

You already know that the drug has two release forms. In this case, the drug "Spazmalgon" is prescribed to children more often for intramuscular or In each individual case, a separate dosage and duration of treatment is selected.

Injections

Treatment with this remedy should not last more than five days. If the doctor has established his own course of treatment, then it is necessary to monitor the condition of the liver.

Can there be negative reactions to the medicine?

Like any other drug, Spazmalgon has side effects. Among them are the following:

allergies (manifested by urticaria, itching of mucous membranes or;
heart reaction (increased heart rate, abnormal blood pressure, dizziness or fainting);
reaction of the circulatory system (observed only with prolonged uncontrolled use of the drug);
reaction of the respiratory system (shortness of breath, bronchospasm).

Can the medicine be used with other drugs?

When using the medicine, you should refrain from taking antipyretic drugs. Because otherwise, an overdose of the active substance may occur and a negative reaction may occur.

"Spazmalgon": analogues

Currently, manufacturers produce a wide variety of non-steroidal anti-inflammatory drugs. So, among them we can highlight “Nurofen”, “Solpadein”, “Spazgan” and many others.

Price category

Spasmalgon is a drug belonging to the category of non-narcotic substances. Spazmalgon is sold in pharmacies without a prescription, is widely used by the population to relieve spastic pain, and few consumers are familiar with the instructions for using this drug. Meanwhile, it also has contraindications for use; it can cause side effects, and the dosage must be strictly observed.

Table of contents:

Composition of Spazmalgon, dosage forms and pharmacological action

The drug in question is available in the form of tablets and solution for intramuscular or intravenous administration. Composition of Spazmalgon combined:

fenpiverinium bromide;
metamizole sodium;
pitofenone.

This combination of analgesic and antispasmodic components leads to an increase in their pharmacological action:

Pitophenone hydrochloride has a direct myotropic effect on smooth muscles; this component acts on the principle of papaverine.
Metamizole sodium - this substance is a derivative of pyrazolone and has not only an analgesic, but also an antipyretic effect.
Phenpiverinium bromide is capable of blocking choline receptors, which determines the myotropic effect of the component on smooth muscles.

Indications and features of the use of Spazmalgon

Many people take a Spazmalgon tablet “with or without reason” - their stomach hurts, they feel heaviness in their head, their muscles “ache.” In fact, in the official instructions for the drug in question there is a clear differentiation of the conditions for which Spazmalgon should be taken:

It is also possible to take the drug in question in case of acute sciatica, but only as a short-term treatment.

The doctor may prescribe Spazmalgon during the recovery period after surgery, or after diagnostic procedures that are accompanied by pain.

Special instructions for use

Taking the drug in question also has some features - these are not just recommendations, but instructions that should be strictly followed:

Contraindications to the use of Spazmalgon, possible side effects

The tablet form of the drug in question is strictly prohibited for the following pathologies:

prostatic hyperplasia;
pregnancy and lactation;
chronic form of the course;
inhibition of bone marrow hematopoiesis;
megacolon;
children under 5 years of age.

Intravenous administration of Spazmalgon is not given to children under 3 months of age or in cases of low body weight (less than 5 kg). Spazmalgon should be taken with extreme caution by people who have a tendency to.

Possible side effects

If the patient is allergic to the components of the drug in question, then it is not prescribed. But even in the absence of hypersensitivity or individual intolerance to the components of Spazmalgon, the following side effects may occur during treatment:

impaired renal function (for example, increased urination or anuria);
increased body temperature for no apparent reason, difficulty swallowing are signs of agranulocytosis.

If Spazmalgon is administered intravenously or intramuscularly, then an infiltrate (compaction) may form at the injection site.

Spazmalgon dosage

The tablet form of the drug in question is taken by adults and children over 15 years of age at a dose of 1-2 tablets 3 times a day. If Spazmalgon is required for children aged 12-15 years, then 1 tablet can be taken per dose, but no more than 6 tablets per day. Children aged 8-12 years mean taking no more than 4 tablets per day (one for each use), and at the age of 5-7 years the maximum permissible daily dose is 2 tablets (half a tablet 4 times a day).

The injection solution is administered intravenously for acute severe colic, 2 ml, very slowly - at least 60 seconds per 1 ml of the drug. A maximum of 5 ml of solution is injected intramuscularly three times a day.

Note:the daily dose of Spazmalgon solution should not exceed 10 ml, and the duration of treatment by injection can be 5 days or no more.

12-15 years – maximum 1 ml intramuscularly or intravenously;
8-12 years – 0.6 ml intravenously, 0.7 ml intramuscularly;
5-7 years – 0.4 ml intravenously, 0.5 ml intramuscularly;
3-4 years – 0.3 ml intravenously, 0.4 ml intramuscularly;
1-2 years – 0.2 ml intravenously, 0.3 ml intramuscularly;
3-11 months - administered only intramuscularly in a maximum daily dose of 0.2 ml.

Overdose

Most often, an overdose of Spazmalgon occurs when it is introduced into the body by injection. Symptoms of this condition will be pronounced